APRE vs VXZ: Correlation
How closely do Aprea Therapeutics, Inc. (APRE) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) trade together? Their weekly returns over three years give a correlation of -0.35, which is negative.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are APRE and VXZ?
On 3 years of weekly data the APRE/VXZ correlation comes out at -0.35, negative, meaning they tend to move in opposite directions. The relationship has been stable: the 1-year correlation (-0.30) sits close to the 3-year figure. The 5-year figure is -0.28, and annualized covariance runs at -729.8 %².
VXZ is close to the least connected end of APRE's tracked universe, ranking #10 of 10. The last year tells two different stories: VXZ led by 30.1 percentage points, -46.2% for APRE against -16.1% for VXZ. Risk is not evenly split, since APRE carries 3.2 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
APRE vs VXZ: side by side
| APRE (Aprea Therapeutics, Inc.) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | -46.2% | -16.1% |
| 5-year return | -99.0% | -53.1% |
| Volatility (ann.) | 82.1% | 25.6% |
| Beta vs S&P 500 | 2.10 | -1.31 |
| Max drawdown (3Y) | -93.0% | -36.4% |
| Market cap | – | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | APRE | VXZ |
|---|---|---|
| 2022 | -88.5% | +0.5% |
| 2023 | -29.0% | -44.0% |
| 2024 | -30.0% | -12.7% |
| 2025 | -74.1% | +5.7% |
| 2026 | +0.8% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are APRE and VXZ good diversifiers for each other?
Yes: at -0.35, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between APRE and VXZ?
As of 2026-08-27, the correlation of weekly returns between APRE and VXZ is -0.35 over 3 years, -0.30 over 1 year and -0.28 over 5 years.
Is VXZ a good diversifier for APRE?
Yes: at -0.35, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.35 mean?
On the −1 to +1 scale, -0.35 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/apre-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/apre-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: APRE correlations · VXZ correlations
