APRE vs PRQR: Correlation
Measured on weekly returns over the past three years, Aprea Therapeutics, Inc. (APRE) and ProQR Therapeutics N.V. (PRQR) carry a correlation of 0.49, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are APRE and PRQR?
Over the past 3 years, APRE and PRQR moved with a correlation of 0.49, which is moderate. Lately the two have drifted apart, with the 1-year correlation at 0.21 versus 0.49 over 3 years. Over 5 years the correlation is 0.33, and the annualized covariance of weekly returns is 4185.7 %².
In APRE's tracked universe of 10 assets, PRQR sits right near the top at #1. Their recent paths diverged sharply: over the last 12 months PRQR outperformed by 51.2 percentage points (-46.2% for APRE against +5.0% for PRQR).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
APRE vs PRQR: side by side
| APRE (Aprea Therapeutics, Inc.) | PRQR (ProQR Therapeutics N.V.) | |
|---|---|---|
| 1-year return | -46.2% | +5.0% |
| 5-year return | -99.0% | -64.2% |
| Volatility (ann.) | 82.1% | 104.9% |
| Beta vs S&P 500 | 2.10 | 1.98 |
| Max drawdown (3Y) | -93.0% | -75.1% |
| Market cap | – | $0.3B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | APRE | PRQR |
|---|---|---|
| 2022 | -88.5% | -53.8% |
| 2023 | -29.0% | -46.5% |
| 2024 | -30.0% | +33.8% |
| 2025 | -74.1% | -23.8% |
| 2026 | +0.8% | +14.9% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are APRE and PRQR good diversifiers for each other?
A fair diversifier. At 0.49, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between APRE and PRQR?
Using weekly returns as of 2026-08-27: 0.49 over 3 years, with 0.21 over the last year and 0.33 over 5 years.
Is PRQR a good diversifier for APRE?
A fair diversifier. At 0.49, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.49 mean?
A reading of 0.49 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/apre-vs-prqr.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/apre-vs-prqr/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: APRE correlations · PRQR correlations
