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APGE vs DFTX: Correlation

How closely do Apogee Therapeutics, Inc. (APGE) and Definium Therapeutics, Inc. (DFTX) trade together? Their weekly returns over three years give a correlation of 0.51, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.51
moderate
Correlation (1Y)
0.56
last 12 months
Correlation (5Y)
n/a
long-run
Ann. covariance
3852.2
%² · weekly, annualized

How correlated are APGE and DFTX?

On 3 years of weekly data the APGE/DFTX correlation comes out at 0.51, moderate. Little has changed lately, as the 1-year reading of 0.56 lands near the 3-year figure. The 5-year figure is n/a, and annualized covariance runs at 3852.2 %².

DFTX is one of the assets that tracks APGE most closely: it ranks #2 out of the 14 assets we track against APGE. Their recent paths diverged sharply: over the last 12 months DFTX outperformed by 87.8 percentage points (+257.1% for APGE against +344.9% for DFTX).

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

APGE vs DFTX: side by side

APGE (Apogee Therapeutics, Inc.)DFTX (Definium Therapeutics, Inc.)
1-year return+257.1%+344.9%
5-year returnn/a+4.7%
Volatility (ann.)82.6%90.9%
Beta vs S&P 5001.061.35
Max drawdown (3Y)-58.8%-58.4%
Market cap$10.2B$5.9B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: DFTX -58.4% vs -58.8%
-4%0%+410%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. APGE · DFTX

Year-by-year returns

YearAPGEDFTX
2022-89.4%
2023+66.4%
2024+62.1%+90.2%
2025+66.6%+92.4%
2026+78.8%+227.3%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are APGE and DFTX good diversifiers for each other?

To a limited degree. At 0.51 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.

FAQ

What is the correlation between APGE and DFTX?

The APGE/DFTX correlation stands at 0.51 on a 3-year window (1 year: 0.56, 5 years: n/a), computed from weekly returns as of 2026-08-27.

Is DFTX a good diversifier for APGE?

To a limited degree. At 0.51 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.

What does a correlation of 0.51 mean?

On the −1 to +1 scale, 0.51 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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$ curl https://www.pairbook.io/api/v1/pairs/apge-vs-dftx.json

APGE vs DFTX: 3-year weekly correlation 0.51APGE vs DFTX0.51

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Related comparisons

Hubs: APGE correlations · DFTX correlations