AEMD vs IONS: Correlation
How closely do Aethlon Medical, Inc. (AEMD) and Ionis Pharmaceuticals, Inc. (IONS) trade together? Their weekly returns over three years give a correlation of -0.22, which is negative.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are AEMD and IONS?
On 3 years of weekly data the AEMD/IONS correlation comes out at -0.22, negative, meaning they tend to move in opposite directions. The past 12 months show a weaker link (-0.46) than the 3-year average (-0.22). The 5-year figure is 0.01, and annualized covariance runs at -1133.5 %².
Out of 10 assets tracked against AEMD, IONS lands near the bottom at #9. Their recent paths diverged sharply: over the last 12 months IONS outperformed by 143.3 percentage points (-97.3% for AEMD against +46.0% for IONS). Risk is not evenly split, since AEMD carries 2.6 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
AEMD vs IONS: side by side
| AEMD (Aethlon Medical, Inc.) | IONS (Ionis Pharmaceuticals, Inc.) | |
|---|---|---|
| 1-year return | -97.3% | +46.0% |
| 5-year return | -100.0% | +59.5% |
| Volatility (ann.) | 117.3% | 44.7% |
| Beta vs S&P 500 | 1.45 | 0.72 |
| Max drawdown (3Y) | -99.8% | -52.4% |
| Market cap | – | $10.4B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | AEMD | IONS |
|---|---|---|
| 2022 | -84.9% | +24.1% |
| 2023 | -21.8% | +33.9% |
| 2024 | -60.7% | -30.9% |
| 2025 | -96.0% | +126.3% |
| 2026 | -84.3% | -21.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are AEMD and IONS good diversifiers for each other?
By historical standards, yes. A correlation of -0.22 means the two rarely move for the same reasons.
FAQ
What is the correlation between AEMD and IONS?
Using weekly returns as of 2026-08-27: -0.22 over 3 years, with -0.46 over the last year and 0.01 over 5 years.
Is IONS a good diversifier for AEMD?
By historical standards, yes. A correlation of -0.22 means the two rarely move for the same reasons.
What does a correlation of -0.22 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/aemd-vs-ions.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/aemd-vs-ions/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: AEMD correlations · IONS correlations
