ACIU vs VXZ: Correlation
AC Immune SA (ACIU) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) show a negative relationship: their 3-year correlation of weekly returns is -0.28.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ACIU and VXZ?
Across a 3-year window, the weekly returns of ACIU and VXZ correlate at -0.28, negative, meaning they tend to move in opposite directions. The relationship has been stable: the 1-year correlation (-0.23) sits close to the 3-year figure. Stretching to 5 years gives -0.30, with an annualized covariance of -488.4 %².
VXZ is close to the least connected end of ACIU's tracked universe, ranking #10 of 11. Correlation aside, the last 12 months split them widely, with ACIU ahead by 47.0 points (+30.9% versus -16.1%). One caveat on sizing: ACIU is 2.7 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ACIU vs VXZ: side by side
| ACIU (AC Immune SA) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | +30.9% | -16.1% |
| 5-year return | -61.2% | -53.1% |
| Volatility (ann.) | 69.0% | 25.6% |
| Beta vs S&P 500 | 1.20 | -1.31 |
| Max drawdown (3Y) | -70.4% | -36.4% |
| Market cap | $0.3B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | ACIU | VXZ |
|---|---|---|
| 2022 | -58.8% | +0.5% |
| 2023 | +145.1% | -44.0% |
| 2024 | -46.0% | -12.7% |
| 2025 | +16.3% | +5.7% |
| 2026 | -13.7% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ACIU and VXZ good diversifiers for each other?
By historical standards, yes. A correlation of -0.28 means the two rarely move for the same reasons.
FAQ
What is the correlation between ACIU and VXZ?
As of 2026-08-27, the correlation of weekly returns between ACIU and VXZ is -0.28 over 3 years, -0.23 over 1 year and -0.30 over 5 years.
Is VXZ a good diversifier for ACIU?
By historical standards, yes. A correlation of -0.28 means the two rarely move for the same reasons.
What does a correlation of -0.28 mean?
On the −1 to +1 scale, -0.28 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/aciu-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/aciu-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: ACIU correlations · VXZ correlations
