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ACIU vs LYEL: Correlation

AC Immune SA (ACIU) and Lyell Immunopharma, Inc. (LYEL) show a moderate relationship: their 3-year correlation of weekly returns is 0.45.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.45
moderate
Correlation (1Y)
0.51
last 12 months
Correlation (5Y)
0.39
long-run
Ann. covariance
3103.8
%² · weekly, annualized

How correlated are ACIU and LYEL?

Across a 3-year window, the weekly returns of ACIU and LYEL correlate at 0.45, moderate. Little has changed lately, as the 1-year reading of 0.51 lands near the 3-year figure. Stretching to 5 years gives 0.39, with an annualized covariance of 3103.8 %².

Few assets follow ACIU as closely as LYEL, which ranks #1 of 11 tracked partners. Their 12-month results are close: +30.9% for ACIU against +29.5% for LYEL.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

ACIU vs LYEL: side by side

ACIU (AC Immune SA)LYEL (Lyell Immunopharma, Inc.)
1-year return+30.9%+29.5%
5-year return-61.2%-95.4%
Volatility (ann.)69.0%99.9%
Beta vs S&P 5001.202.09
Max drawdown (3Y)-70.4%-87.3%
Market cap$0.3B$0.4B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: ACIU -70.4% vs -87.3%Higher 5y return: ACIU -61.2% vs -95.4%
-4%0%+189%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. ACIU · LYEL

Year-by-year returns

YearACIULYEL
2022-58.8%-55.2%
2023+145.1%-44.1%
2024-46.0%-67.0%
2025+16.3%+140.5%
2026-13.7%-52.5%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are ACIU and LYEL good diversifiers for each other?

Reasonably. At 0.45, ACIU and LYEL keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between ACIU and LYEL?

As of 2026-08-27, the correlation of weekly returns between ACIU and LYEL is 0.45 over 3 years, 0.51 over 1 year and 0.39 over 5 years.

Is LYEL a good diversifier for ACIU?

Reasonably. At 0.45, ACIU and LYEL keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.45 mean?

On the −1 to +1 scale, 0.45 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

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ACIU vs LYEL: 3-year weekly correlation 0.45ACIU vs LYEL0.45

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Related comparisons

Hubs: ACIU correlations · LYEL correlations