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XNCR vs ZYME: Correlation

Measured on weekly returns over the past three years, Xencor, Inc. (XNCR) and Zymeworks Inc. (ZYME) carry a correlation of 0.51, a moderate link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.51
moderate
Correlation (1Y)
0.35
last 12 months
Correlation (5Y)
0.38
long-run
Ann. covariance
1543.5
%² · weekly, annualized

How correlated are XNCR and ZYME?

On 3 years of weekly data the XNCR/ZYME correlation comes out at 0.51, moderate. The link has loosened recently: the 1-year correlation (0.35) runs below the 3-year figure (0.51). The 5-year figure is 0.38, and annualized covariance runs at 1543.5 %².

By 3-year correlation, ZYME places #6 of the 15 assets tracked against XNCR. The last year tells two different stories: XNCR led by 165.8 percentage points, +260.1% for XNCR against +94.3% for ZYME.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

XNCR vs ZYME: side by side

XNCR (Xencor, Inc.)ZYME (Zymeworks Inc.)
1-year return+260.1%+94.3%
5-year return-14.8%-10.9%
Volatility (ann.)60.9%49.4%
Beta vs S&P 5001.371.02
Max drawdown (3Y)-73.9%-45.7%
Market cap$2.1B$2.1B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: ZYME -45.7% vs -73.9%Higher 5y return: ZYME -10.9% vs -14.8%
0%+238%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). XNCR · ZYME

Year-by-year returns

YearXNCRZYME
2022-35.1%-52.0%
2023-18.5%+32.2%
2024+8.2%+40.9%
2025-33.4%+79.8%
2026+88.6%+10.2%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are XNCR and ZYME good diversifiers for each other?

To a limited degree. At 0.51 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.

FAQ

What is the correlation between XNCR and ZYME?

The XNCR/ZYME correlation stands at 0.51 on a 3-year window (1 year: 0.35, 5 years: 0.38), computed from weekly returns as of 2026-08-27.

Is ZYME a good diversifier for XNCR?

To a limited degree. At 0.51 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.

What does a correlation of 0.51 mean?

On the −1 to +1 scale, 0.51 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/xncr-vs-zyme.json

XNCR vs ZYME: 3-year weekly correlation 0.51XNCR vs ZYME0.51

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Related comparisons

Hubs: XNCR correlations · ZYME correlations