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WST vs XLO: Correlation

West Pharmaceutical Services (WST) and Xilio Therapeutics, Inc. (XLO) show a negative relationship: their 3-year correlation of weekly returns is -0.22.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.22
negative
Correlation (1Y)
0.14
last 12 months
Correlation (5Y)
-0.02
long-run
Ann. covariance
-826.0
%² · weekly, annualized

How correlated are WST and XLO?

Across a 3-year window, the weekly returns of WST and XLO correlate at -0.22, negative, meaning they tend to move in opposite directions. The link has tightened recently: the 1-year correlation (0.14) runs above the 3-year figure (-0.22). Stretching to 5 years gives -0.02, with an annualized covariance of -826.0 %².

Within WST's tracked universe of 36 assets, XLO comes in at #25 by 3-year correlation. The last year tells two different stories: WST led by 47.1 percentage points, +41.1% for WST against -6.0% for XLO. Risk is not evenly split, since XLO carries 2.5 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

WST vs XLO: side by side

WST (West Pharmaceutical Services)XLO (Xilio Therapeutics, Inc.)
1-year return+41.1%-6.0%
5-year return-22.4%-96.0%
Volatility (ann.)38.6%96.4%
Beta vs S&P 5000.86-0.07
Max drawdown (3Y)-53.8%-82.8%
Market cap$24.4B$0.1B
P/E (trailing)44.8
Dividend yield0.25%0.00%
Sector / categoryHealth CareUS Listed
Higher yield: WST 0.25% vs 0.00%Smaller drawdown: WST -53.8% vs -82.8%Higher 5y return: WST -22.4% vs -96.0%
-27%0%+46%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. WST · XLO

Year-by-year returns

YearWSTXLO
2022-49.7%-83.2%
2023+50.0%-79.6%
2024-6.8%+73.6%
2025-15.7%-33.0%
2026+26.1%+0.6%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are WST and XLO good diversifiers for each other?

Yes. With a correlation of -0.22, WST and XLO have moved largely independently, which makes them a genuinely diversifying pair by historical standards.

FAQ

What is the correlation between WST and XLO?

Using weekly returns as of 2026-08-27: -0.22 over 3 years, with 0.14 over the last year and -0.02 over 5 years.

Is XLO a good diversifier for WST?

Yes. With a correlation of -0.22, WST and XLO have moved largely independently, which makes them a genuinely diversifying pair by historical standards.

What does a correlation of -0.22 mean?

A reading of -0.22 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/wst-vs-xlo.json

WST vs XLO: 3-year weekly correlation -0.22WST vs XLO-0.22

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Hubs: WST correlations · XLO correlations