TYRA vs VXZ: Correlation
Measured on weekly returns over the past three years, Tyra Biosciences, Inc. (TYRA) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) carry a correlation of -0.27, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are TYRA and VXZ?
On 3 years of weekly data the TYRA/VXZ correlation comes out at -0.27, negative, meaning they tend to move in opposite directions. Lately the two have moved closer together, with the 1-year correlation at 0.11 versus -0.27 over 3 years. The 5-year figure is -0.25, and annualized covariance runs at -456.1 %².
Out of 10 assets tracked against TYRA, VXZ lands near the bottom at #10. Correlation aside, the last 12 months split them widely, with TYRA ahead by 119.0 points (+102.9% versus -16.1%). Note the risk asymmetry: TYRA runs 2.6 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
TYRA vs VXZ: side by side
| TYRA (Tyra Biosciences, Inc.) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | +102.9% | -16.1% |
| 5-year return | +0.5% | -53.1% |
| Volatility (ann.) | 66.7% | 25.6% |
| Beta vs S&P 500 | 1.45 | -1.31 |
| Max drawdown (3Y) | -75.3% | -36.4% |
| Market cap | $1.6B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | TYRA | VXZ |
|---|---|---|
| 2022 | -46.0% | +0.5% |
| 2023 | +82.2% | -44.0% |
| 2024 | +0.4% | -12.7% |
| 2025 | +89.1% | +5.7% |
| 2026 | -0.6% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are TYRA and VXZ good diversifiers for each other?
Yes: at -0.27, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between TYRA and VXZ?
Using weekly returns as of 2026-08-27: -0.27 over 3 years, with 0.11 over the last year and -0.25 over 5 years.
Is VXZ a good diversifier for TYRA?
Yes: at -0.27, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.27 mean?
On the −1 to +1 scale, -0.27 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/tyra-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/tyra-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: TYRA correlations · VXZ correlations
