TXMD vs VXZ: Correlation
How closely do TherapeuticsMD, Inc. (TXMD) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) trade together? Their weekly returns over three years give a correlation of -0.24, which is negative.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are TXMD and VXZ?
Across a 3-year window, the weekly returns of TXMD and VXZ correlate at -0.24, negative, meaning they tend to move in opposite directions. Lately the two have moved closer together, with the 1-year correlation at -0.10 versus -0.24 over 3 years. Stretching to 5 years gives -0.08, with an annualized covariance of -455.2 %².
Out of 10 assets tracked against TXMD, VXZ lands near the bottom at #10. Correlation aside, the last 12 months split them widely, with TXMD ahead by 114.3 points (+98.2% versus -16.1%). Note the risk asymmetry: TXMD runs 2.9 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
TXMD vs VXZ: side by side
| TXMD (TherapeuticsMD, Inc.) | VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN) | |
|---|---|---|
| 1-year return | +98.2% | -16.1% |
| 5-year return | -94.4% | -53.1% |
| Volatility (ann.) | 73.0% | 25.6% |
| Beta vs S&P 500 | 1.30 | -1.31 |
| Max drawdown (3Y) | -81.2% | -36.4% |
| Market cap | – | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | – |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | TXMD | VXZ |
|---|---|---|
| 2022 | -68.9% | +0.5% |
| 2023 | -59.7% | -44.0% |
| 2024 | -61.8% | -12.7% |
| 2025 | +89.5% | +5.7% |
| 2026 | +36.2% | -10.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are TXMD and VXZ good diversifiers for each other?
By historical standards, yes. A correlation of -0.24 means the two rarely move for the same reasons.
FAQ
What is the correlation between TXMD and VXZ?
The TXMD/VXZ correlation stands at -0.24 on a 3-year window (1 year: -0.10, 5 years: -0.08), computed from weekly returns as of 2026-08-27.
Is VXZ a good diversifier for TXMD?
By historical standards, yes. A correlation of -0.24 means the two rarely move for the same reasons.
What does a correlation of -0.24 mean?
A reading of -0.24 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/txmd-vs-vxz.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/txmd-vs-vxz/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: TXMD correlations · VXZ correlations
