SPRB vs VTV: Correlation
Spruce Biosciences, Inc. (SPRB) and Vanguard Value ETF (VTV) show a negative relationship: their 3-year correlation of weekly returns is -0.13.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SPRB and VTV?
On 3 years of weekly data the SPRB/VTV correlation comes out at -0.13, negative, meaning they tend to move in opposite directions. The past 12 months show a weaker link (-0.32) than the 3-year average (-0.13). The 5-year figure is -0.07, and annualized covariance runs at -1634.5 %².
Within SPRB's tracked universe of 67 assets, VTV comes in at #20 by 3-year correlation. Correlation aside, the last 12 months split them widely, with SPRB ahead by 720.6 points (+746.3% versus +25.7%). Risk is not evenly split, since SPRB carries 91.3 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SPRB vs VTV: side by side
| SPRB (Spruce Biosciences, Inc.) | VTV (Vanguard Value ETF) | |
|---|---|---|
| 1-year return | +746.3% | +25.7% |
| 5-year return | -99.8% | +79.1% |
| Volatility (ann.) | 1086.4% | 11.9% |
| Beta vs S&P 500 | -7.82 | 0.65 |
| Max drawdown (3Y) | -100.0% | -14.5% |
| Market cap | $0.2B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.86% |
| Expense ratio | – | 0.03% |
| Assets under management | – | $256.4B |
| Sector / category | US Listed | ETF · US Style |
On the fund side, VTV sits in the Large Value category at Vanguard, with $256.4B under management, 308 holdings, a 0.03% expense ratio, a 1.86% trailing dividend yield.
Year-by-year returns
| Year | SPRB | VTV |
|---|---|---|
| 2022 | -75.4% | -2.1% |
| 2023 | +167.1% | +9.3% |
| 2024 | -85.7% | +16.0% |
| 2025 | -96.3% | +15.3% |
| 2026 | -27.3% | +19.3% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SPRB and VTV good diversifiers for each other?
By historical standards, yes. A correlation of -0.13 means the two rarely move for the same reasons.
FAQ
What is the correlation between SPRB and VTV?
Using weekly returns as of 2026-08-27: -0.13 over 3 years, with -0.32 over the last year and -0.07 over 5 years.
Is VTV a good diversifier for SPRB?
By historical standards, yes. A correlation of -0.13 means the two rarely move for the same reasons.
What does a correlation of -0.13 mean?
On the −1 to +1 scale, -0.13 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/sprb-vs-vtv.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/sprb-vs-vtv/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: SPRB correlations · VTV correlations
