SPRB vs SPYV: Correlation
Spruce Biosciences, Inc. (SPRB) and SPDR Portfolio S&P 500 Value ETF (SPYV) show a negative relationship: their 3-year correlation of weekly returns is -0.13.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SPRB and SPYV?
Over the past 3 years, SPRB and SPYV moved with a correlation of -0.13, which is negative, meaning they tend to move in opposite directions. The link has loosened recently: the 1-year correlation (-0.33) runs below the 3-year figure (-0.13). Over 5 years the correlation is -0.07, and the annualized covariance of weekly returns is -1686.0 %².
Among the 67 assets we track against SPRB, SPYV ranks #18 by 3-year correlation. Correlation aside, the last 12 months split them widely, with SPRB ahead by 727.8 points (+746.3% versus +18.5%). Risk is not evenly split, since SPRB carries 89.8 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SPRB vs SPYV: side by side
| SPRB (Spruce Biosciences, Inc.) | SPYV (SPDR Portfolio S&P 500 Value ETF) | |
|---|---|---|
| 1-year return | +746.3% | +18.5% |
| 5-year return | -99.8% | +73.5% |
| Volatility (ann.) | 1086.4% | 12.1% |
| Beta vs S&P 500 | -7.82 | 0.70 |
| Max drawdown (3Y) | -100.0% | -17.5% |
| Market cap | $0.2B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.69% |
| Expense ratio | – | 0.04% |
| Assets under management | – | $36.2B |
| Sector / category | US Listed | ETF · US Style |
SPYV, State Street Investment Management's Large Value fund, carries $36.2B under management, 438 holdings, a 0.04% expense ratio, a 1.69% trailing dividend yield.
Year-by-year returns
| Year | SPRB | SPYV |
|---|---|---|
| 2022 | -75.4% | -5.3% |
| 2023 | +167.1% | +22.2% |
| 2024 | -85.7% | +12.2% |
| 2025 | -96.3% | +13.2% |
| 2026 | -27.3% | +12.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SPRB and SPYV good diversifiers for each other?
Yes. With a correlation of -0.13, SPRB and SPYV have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
FAQ
What is the correlation between SPRB and SPYV?
The SPRB/SPYV correlation stands at -0.13 on a 3-year window (1 year: -0.33, 5 years: -0.07), computed from weekly returns as of 2026-08-27.
Is SPYV a good diversifier for SPRB?
Yes. With a correlation of -0.13, SPRB and SPYV have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
What does a correlation of -0.13 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/sprb-vs-spyv.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/sprb-vs-spyv/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: SPRB correlations · SPYV correlations
