SHPH vs SPY: Correlation
Shuttle Pharmaceuticals Holdings, Inc. (SHPH) and SPDR S&P 500 ETF Trust (SPY) show a weak relationship: their 3-year correlation of weekly returns is 0.14.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are SHPH and SPY?
On 3 years of weekly data the SHPH/SPY correlation comes out at 0.14, weak. Lately the two have moved closer together, with the 1-year correlation at 0.29 versus 0.14 over 3 years. The 5-year figure is 0.25, and annualized covariance runs at 207.6 %².
SPY is close to the least connected end of SHPH's tracked universe, ranking #6 of 10. The last year tells two different stories: SPY led by 109.0 percentage points, -88.4% for SHPH against +20.6% for SPY. Risk is not evenly split, since SHPH carries 6.9 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
SHPH vs SPY: side by side
| SHPH (Shuttle Pharmaceuticals Holdings, Inc.) | SPY (SPDR S&P 500 ETF Trust) | |
|---|---|---|
| 1-year return | -88.4% | +20.6% |
| 5-year return | n/a | +82.4% |
| Volatility (ann.) | 99.7% | 14.5% |
| Beta vs S&P 500 | 0.99 | 1.00 |
| Max drawdown (3Y) | -99.8% | -18.8% |
| Market cap | – | – |
| P/E (trailing) | 35.3 | – |
| Dividend yield | 0.00% | 1.01% |
| Expense ratio | – | 0.09% |
| Assets under management | – | $795.3B |
| Sector / category | US Listed | ETF · US Large Cap |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | SHPH | SPY |
|---|---|---|
| 2022 | – | -18.2% |
| 2023 | -76.8% | +26.2% |
| 2024 | -76.4% | +24.9% |
| 2025 | -91.6% | +17.7% |
| 2026 | -78.4% | +13.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are SHPH and SPY good diversifiers for each other?
Yes: at 0.14, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between SHPH and SPY?
As of 2026-08-27, the correlation of weekly returns between SHPH and SPY is 0.14 over 3 years, 0.29 over 1 year and 0.25 over 5 years.
Is SPY a good diversifier for SHPH?
Yes: at 0.14, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of 0.14 mean?
On the −1 to +1 scale, 0.14 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
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Related comparisons
Hubs: SHPH correlations · SPY correlations
