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SCLX vs SPY: Correlation

Scilex Holding Company (SCLX) and SPDR S&P 500 ETF Trust (SPY) show a weak relationship: their 3-year correlation of weekly returns is 0.12.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.12
weak
Correlation (1Y)
0.17
last 12 months
Correlation (5Y)
0.12
long-run
Ann. covariance
221.4
%² · weekly, annualized

How correlated are SCLX and SPY?

Across a 3-year window, the weekly returns of SCLX and SPY correlate at 0.12, weak. Little has changed lately, as the 1-year reading of 0.17 lands near the 3-year figure. Stretching to 5 years gives 0.12, with an annualized covariance of 221.4 %².

Among the 10 assets we track against SCLX, SPY sits near the bottom by co-movement, at rank #7. The last year tells two different stories: SPY led by 71.0 percentage points, -50.4% for SCLX against +20.6% for SPY. One caveat on sizing: SCLX is 8.7 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

SCLX vs SPY: side by side

SCLX (Scilex Holding Company)SPY (SPDR S&P 500 ETF Trust)
1-year return-50.4%+20.6%
5-year return-97.4%+82.4%
Volatility (ann.)125.7%14.5%
Beta vs S&P 5001.061.00
Max drawdown (3Y)-96.4%-18.8%
Market cap
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -96.4%Higher 5y return: SPY +82.4% vs -97.4%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-73%0%+28%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. SCLX · SPY

Year-by-year returns

YearSCLXSPY
2022-60.3%-18.2%
2023-48.9%+26.2%
2024-79.1%+24.9%
2025-18.2%+17.7%
2026-26.7%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are SCLX and SPY good diversifiers for each other?

Yes: at 0.12, the two have gone their own ways historically, which is what genuine diversification looks like.

FAQ

What is the correlation between SCLX and SPY?

Using weekly returns as of 2026-08-27: 0.12 over 3 years, with 0.17 over the last year and 0.12 over 5 years.

Is SPY a good diversifier for SCLX?

Yes: at 0.12, the two have gone their own ways historically, which is what genuine diversification looks like.

What does a correlation of 0.12 mean?

A reading of 0.12 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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SCLX vs SPY: 3-year weekly correlation 0.12SCLX vs SPY0.12

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Hubs: SCLX correlations · SPY correlations