REVB vs SPRO: Correlation
How closely do Revelation Biosciences, Inc. (REVB) and Spero Therapeutics, Inc. (SPRO) trade together? Their weekly returns over three years give a correlation of -0.25, which is negative.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are REVB and SPRO?
Over the past 3 years, REVB and SPRO moved with a correlation of -0.25, which is negative, meaning they tend to move in opposite directions. Lately the two have moved closer together, with the 1-year correlation at 0.08 versus -0.25 over 3 years. Over 5 years the correlation is -0.14, and the annualized covariance of weekly returns is -4563.7 %².
SPRO is close to the least connected end of REVB's tracked universe, ranking #9 of 10. Their recent paths diverged sharply: over the last 12 months SPRO outperformed by 51.7 percentage points (-90.6% for REVB against -38.9% for SPRO).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
REVB vs SPRO: side by side
| REVB (Revelation Biosciences, Inc.) | SPRO (Spero Therapeutics, Inc.) | |
|---|---|---|
| 1-year return | -90.6% | -38.9% |
| 5-year return | -100.0% | -93.3% |
| Volatility (ann.) | 113.3% | 159.8% |
| Beta vs S&P 500 | 0.65 | 1.61 |
| Max drawdown (3Y) | -100.0% | -68.9% |
| Market cap | – | $0.1B |
| P/E (trailing) | 0.0 | 8.6 |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | REVB | SPRO |
|---|---|---|
| 2022 | -98.1% | -89.2% |
| 2023 | -92.5% | -15.0% |
| 2024 | -96.9% | -29.9% |
| 2025 | -96.4% | +126.2% |
| 2026 | -67.8% | -48.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are REVB and SPRO good diversifiers for each other?
Yes. With a correlation of -0.25, REVB and SPRO have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
FAQ
What is the correlation between REVB and SPRO?
Using weekly returns as of 2026-08-27: -0.25 over 3 years, with 0.08 over the last year and -0.14 over 5 years.
Is SPRO a good diversifier for REVB?
Yes. With a correlation of -0.25, REVB and SPRO have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
What does a correlation of -0.25 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/revb-vs-spro.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/revb-vs-spro/)
Free with attribution; caching and terms are described in the API documentation.
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Hubs: REVB correlations · SPRO correlations