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REVB vs SPRO: Correlation

How closely do Revelation Biosciences, Inc. (REVB) and Spero Therapeutics, Inc. (SPRO) trade together? Their weekly returns over three years give a correlation of -0.25, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.25
negative
Correlation (1Y)
0.08
last 12 months
Correlation (5Y)
-0.14
long-run
Ann. covariance
-4563.7
%² · weekly, annualized

How correlated are REVB and SPRO?

Over the past 3 years, REVB and SPRO moved with a correlation of -0.25, which is negative, meaning they tend to move in opposite directions. Lately the two have moved closer together, with the 1-year correlation at 0.08 versus -0.25 over 3 years. Over 5 years the correlation is -0.14, and the annualized covariance of weekly returns is -4563.7 %².

SPRO is close to the least connected end of REVB's tracked universe, ranking #9 of 10. Their recent paths diverged sharply: over the last 12 months SPRO outperformed by 51.7 percentage points (-90.6% for REVB against -38.9% for SPRO).

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

REVB vs SPRO: side by side

REVB (Revelation Biosciences, Inc.)SPRO (Spero Therapeutics, Inc.)
1-year return-90.6%-38.9%
5-year return-100.0%-93.3%
Volatility (ann.)113.3%159.8%
Beta vs S&P 5000.651.61
Max drawdown (3Y)-100.0%-68.9%
Market cap$0.1B
P/E (trailing)0.08.6
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Lower P/E: REVB 0.0 vs 8.6Smaller drawdown: SPRO -68.9% vs -100.0%Higher 5y return: SPRO -93.3% vs -100.0%
-92%0%+33%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. REVB · SPRO

Year-by-year returns

YearREVBSPRO
2022-98.1%-89.2%
2023-92.5%-15.0%
2024-96.9%-29.9%
2025-96.4%+126.2%
2026-67.8%-48.1%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are REVB and SPRO good diversifiers for each other?

Yes. With a correlation of -0.25, REVB and SPRO have moved largely independently, which makes them a genuinely diversifying pair by historical standards.

FAQ

What is the correlation between REVB and SPRO?

Using weekly returns as of 2026-08-27: -0.25 over 3 years, with 0.08 over the last year and -0.14 over 5 years.

Is SPRO a good diversifier for REVB?

Yes. With a correlation of -0.25, REVB and SPRO have moved largely independently, which makes them a genuinely diversifying pair by historical standards.

What does a correlation of -0.25 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/revb-vs-spro.json

REVB vs SPRO: 3-year weekly correlation -0.25REVB vs SPRO-0.25

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Hubs: REVB correlations · SPRO correlations