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PTCT vs SPY: Correlation

Measured on weekly returns over the past three years, PTC Therapeutics, Inc. (PTCT) and SPDR S&P 500 ETF Trust (SPY) carry a correlation of 0.34, a moderate link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.34
moderate
Correlation (1Y)
0.31
last 12 months
Correlation (5Y)
0.33
long-run
Ann. covariance
260.1
%² · weekly, annualized

How correlated are PTCT and SPY?

Over the past 3 years, PTCT and SPY moved with a correlation of 0.34, which is moderate. The relationship has been stable: the 1-year correlation (0.31) sits close to the 3-year figure. Over 5 years the correlation is 0.33, and the annualized covariance of weekly returns is 260.1 %².

SPY is close to the least connected end of PTCT's tracked universe, ranking #7 of 11. The last year tells two different stories: PTCT led by 23.7 percentage points, +44.3% for PTCT against +20.6% for SPY. Risk is not evenly split, since PTCT carries 3.6 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

PTCT vs SPY: side by side

PTCT (PTC Therapeutics, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return+44.3%+20.6%
5-year return+70.4%+82.4%
Volatility (ann.)52.5%14.5%
Beta vs S&P 5001.251.00
Max drawdown (3Y)-56.8%-18.8%
Market cap$6.0B
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -56.8%Higher 5y return: SPY +82.4% vs +70.4%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-1%0%+50%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. PTCT · SPY

Year-by-year returns

YearPTCTSPY
2022-4.2%-18.2%
2023-27.8%+26.2%
2024+63.8%+24.9%
2025+68.3%+17.7%
2026-5.5%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are PTCT and SPY good diversifiers for each other?

A fair diversifier. At 0.34, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

FAQ

What is the correlation between PTCT and SPY?

The PTCT/SPY correlation stands at 0.34 on a 3-year window (1 year: 0.31, 5 years: 0.33), computed from weekly returns as of 2026-08-27.

Is SPY a good diversifier for PTCT?

A fair diversifier. At 0.34, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

What does a correlation of 0.34 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

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PTCT vs SPY: 3-year weekly correlation 0.34PTCT vs SPY0.34

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Hubs: PTCT correlations · SPY correlations