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PRAX vs QQQ: Correlation

How closely do Praxis Precision Medicines, Inc. (PRAX) and Invesco QQQ Trust (QQQ) trade together? Their weekly returns over three years give a correlation of 0.17, which is weak.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.17
weak
Correlation (1Y)
0.18
last 12 months
Correlation (5Y)
0.18
long-run
Ann. covariance
580.8
%² · weekly, annualized

How correlated are PRAX and QQQ?

On 3 years of weekly data the PRAX/QQQ correlation comes out at 0.17, weak. Little has changed lately, as the 1-year reading of 0.18 lands near the 3-year figure. The 5-year figure is 0.18, and annualized covariance runs at 580.8 %².

By 3-year correlation, QQQ places #10 of the 15 assets tracked against PRAX. Their recent paths diverged sharply: over the last 12 months PRAX outperformed by 657.7 percentage points (+684.0% for PRAX against +26.3% for QQQ). Note the risk asymmetry: PRAX runs 8.7 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

PRAX vs QQQ: side by side

PRAX (Praxis Precision Medicines, Inc.)QQQ (Invesco QQQ Trust)
1-year return+684.0%+26.3%
5-year return+28.6%+95.4%
Volatility (ann.)170.9%19.6%
Beta vs S&P 5002.131.28
Max drawdown (3Y)-68.6%-22.8%
Market cap$10.3B
P/E (trailing)
Dividend yield0.00%0.44%
Expense ratio0.18%
Assets under management$452.8B
Sector / categoryUS ListedETF · US Growth & Tech
Higher yield: QQQ 0.44% vs 0.00%Smaller drawdown: QQQ -22.8% vs -68.6%Higher 5y return: QQQ +95.4% vs +28.6%

QQQ is a Large Growth fund from Invesco: $452.8B under management, 104 holdings, a 0.18% expense ratio, a 0.44% trailing dividend yield.

-20%0%+702%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. PRAX · QQQ

Year-by-year returns

YearPRAXQQQ
2022-87.9%-32.6%
2023-37.6%+54.9%
2024+245.4%+25.6%
2025+283.0%+20.8%
2026+24.8%+17.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are PRAX and QQQ good diversifiers for each other?

By historical standards, yes. A correlation of 0.17 means the two rarely move for the same reasons.

FAQ

What is the correlation between PRAX and QQQ?

As of 2026-08-27, the correlation of weekly returns between PRAX and QQQ is 0.17 over 3 years, 0.18 over 1 year and 0.18 over 5 years.

Is QQQ a good diversifier for PRAX?

By historical standards, yes. A correlation of 0.17 means the two rarely move for the same reasons.

What does a correlation of 0.17 mean?

A reading of 0.17 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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PRAX vs QQQ: 3-year weekly correlation 0.17PRAX vs QQQ0.17

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Hubs: PRAX correlations · QQQ correlations