PFE vs SPRB: Correlation
Measured on weekly returns over the past three years, Pfizer (PFE) and Spruce Biosciences, Inc. (SPRB) carry a correlation of -0.23, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are PFE and SPRB?
Over the past 3 years, PFE and SPRB moved with a correlation of -0.23, which is negative, meaning they tend to move in opposite directions. The link has loosened recently: the 1-year correlation (-0.40) runs below the 3-year figure (-0.23). Over 5 years the correlation is -0.15, and the annualized covariance of weekly returns is -5886.4 %².
Among the 32 assets we track against PFE, SPRB sits near the bottom by co-movement, at rank #32. Their recent paths diverged sharply: over the last 12 months SPRB outperformed by 726.7 percentage points (+19.6% for PFE against +746.3% for SPRB). Risk is not evenly split, since SPRB carries 45.6 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
PFE vs SPRB: side by side
| PFE (Pfizer) | SPRB (Spruce Biosciences, Inc.) | |
|---|---|---|
| 1-year return | +19.6% | +746.3% |
| 5-year return | -21.9% | -99.8% |
| Volatility (ann.) | 23.8% | 1086.4% |
| Beta vs S&P 500 | 0.40 | -7.82 |
| Max drawdown (3Y) | -34.8% | -100.0% |
| Market cap | $159.7B | $0.2B |
| P/E (trailing) | 37.4 | – |
| Dividend yield | 6.08% | 0.00% |
| Sector / category | Health Care | US Listed |
Year-by-year returns
| Year | PFE | SPRB |
|---|---|---|
| 2022 | -10.4% | -75.4% |
| 2023 | -41.3% | +167.1% |
| 2024 | -2.2% | -85.7% |
| 2025 | +0.6% | -96.3% |
| 2026 | +18.3% | -27.3% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are PFE and SPRB good diversifiers for each other?
By historical standards, yes. A correlation of -0.23 means the two rarely move for the same reasons.
FAQ
What is the correlation between PFE and SPRB?
The PFE/SPRB correlation stands at -0.23 on a 3-year window (1 year: -0.40, 5 years: -0.15), computed from weekly returns as of 2026-08-27.
Is SPRB a good diversifier for PFE?
By historical standards, yes. A correlation of -0.23 means the two rarely move for the same reasons.
What does a correlation of -0.23 mean?
On the −1 to +1 scale, -0.23 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
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Related comparisons
Hubs: PFE correlations · SPRB correlations
