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OSUR vs TWST: Correlation

OraSure Technologies, Inc. (OSUR) and Twist Bioscience Corporation (TWST) show a moderate relationship: their 3-year correlation of weekly returns is 0.44.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.44
moderate
Correlation (1Y)
0.36
last 12 months
Correlation (5Y)
0.32
long-run
Ann. covariance
1357.3
%² · weekly, annualized

How correlated are OSUR and TWST?

Across a 3-year window, the weekly returns of OSUR and TWST correlate at 0.44, moderate. The relationship has been stable: the 1-year correlation (0.36) sits close to the 3-year figure. Stretching to 5 years gives 0.32, with an annualized covariance of 1357.3 %².

Among the 11 assets we track against OSUR, TWST ranks #4 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months TWST outperformed by 452.6 percentage points (+10.5% for OSUR against +463.1% for TWST). Note the risk asymmetry: TWST runs 1.9 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

OSUR vs TWST: side by side

OSUR (OraSure Technologies, Inc.)TWST (Twist Bioscience Corporation)
1-year return+10.5%+463.1%
5-year return-66.1%+39.8%
Volatility (ann.)40.8%76.1%
Beta vs S&P 5000.832.21
Max drawdown (3Y)-74.7%-59.0%
Market cap$0.3B$9.6B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: TWST -59.0% vs -74.7%Higher 5y return: TWST +39.8% vs -66.1%
-30%0%+494%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). OSUR · TWST

Year-by-year returns

YearOSURTWST
2022-44.5%-69.2%
2023+70.1%+54.8%
2024-56.0%+26.1%
2025-33.0%-31.7%
2026+52.5%+382.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are OSUR and TWST good diversifiers for each other?

A fair diversifier. At 0.44, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

FAQ

What is the correlation between OSUR and TWST?

Using weekly returns as of 2026-08-27: 0.44 over 3 years, with 0.36 over the last year and 0.32 over 5 years.

Is TWST a good diversifier for OSUR?

A fair diversifier. At 0.44, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

What does a correlation of 0.44 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/osur-vs-twst.json

OSUR vs TWST: 3-year weekly correlation 0.44OSUR vs TWST0.44

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Related comparisons

Hubs: OSUR correlations · TWST correlations