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OBIO vs SPY: Correlation

Orchestra BioMed Holdings, Inc. (OBIO) and SPDR S&P 500 ETF Trust (SPY) show a moderate relationship: their 3-year correlation of weekly returns is 0.32.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.32
moderate
Correlation (1Y)
0.06
last 12 months
Correlation (5Y)
0.17
long-run
Ann. covariance
365.9
%² · weekly, annualized

How correlated are OBIO and SPY?

On 3 years of weekly data the OBIO/SPY correlation comes out at 0.32, moderate. The link has loosened recently: the 1-year correlation (0.06) runs below the 3-year figure (0.32). The 5-year figure is 0.17, and annualized covariance runs at 365.9 %².

Among the 10 assets we track against OBIO, SPY sits near the bottom by co-movement, at rank #6. Correlation aside, the last 12 months split them widely, with OBIO ahead by 59.3 points (+79.9% versus +20.6%). Note the risk asymmetry: OBIO runs 5.5 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

OBIO vs SPY: side by side

OBIO (Orchestra BioMed Holdings, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return+79.9%+20.6%
5-year return-47.8%+82.4%
Volatility (ann.)79.5%14.5%
Beta vs S&P 5001.751.00
Max drawdown (3Y)-78.2%-18.8%
Market cap$0.3B
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -78.2%Higher 5y return: SPY +82.4% vs -47.8%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-12%0%+95%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. OBIO · SPY

Year-by-year returns

YearOBIOSPY
2022-1.0%-18.2%
2023-8.5%+26.2%
2024-56.2%+24.9%
2025+3.8%+17.7%
2026+23.1%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are OBIO and SPY good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.32 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between OBIO and SPY?

The OBIO/SPY correlation stands at 0.32 on a 3-year window (1 year: 0.06, 5 years: 0.17), computed from weekly returns as of 2026-08-27.

Is SPY a good diversifier for OBIO?

Yes, to a useful degree: a correlation of 0.32 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.32 mean?

A reading of 0.32 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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OBIO vs SPY: 3-year weekly correlation 0.32OBIO vs SPY0.32

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Hubs: OBIO correlations · SPY correlations