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MKTX vs MYGN: Correlation

Measured on weekly returns over the past three years, MarketAxess Holdings, Inc. (MKTX) and Myriad Genetics, Inc. (MYGN) carry a correlation of -0.29, a negative link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.29
negative
Correlation (1Y)
-0.61
last 12 months
Correlation (5Y)
-0.02
long-run
Ann. covariance
-891.7
%² · weekly, annualized

How correlated are MKTX and MYGN?

Over the past 3 years, MKTX and MYGN moved with a correlation of -0.29, which is negative, meaning they tend to move in opposite directions. The link has loosened recently: the 1-year correlation (-0.61) runs below the 3-year figure (-0.29). Over 5 years the correlation is -0.02, and the annualized covariance of weekly returns is -891.7 %².

MYGN is close to the least connected end of MKTX's tracked universe, ranking #13 of 14. Their recent paths diverged sharply: over the last 12 months MKTX outperformed by 34.7 percentage points (-11.7% for MKTX against -46.4% for MYGN). Note the risk asymmetry: MYGN runs 2.1 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

MKTX vs MYGN: side by side

MKTX (MarketAxess Holdings, Inc.)MYGN (Myriad Genetics, Inc.)
1-year return-11.7%-46.4%
5-year return-63.7%-91.1%
Volatility (ann.)37.8%80.5%
Beta vs S&P 5000.211.49
Max drawdown (3Y)-61.8%-90.0%
Market cap$5.7B$0.3B
P/E (trailing)19.2
Dividend yield1.90%0.00%
Sector / categoryUS ListedUS Listed
Higher yield: MKTX 1.90% vs 0.00%Smaller drawdown: MKTX -61.8% vs -90.0%Higher 5y return: MKTX -63.7% vs -91.1%
-57%0%+23%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. MKTX · MYGN

Year-by-year returns

YearMKTXMYGN
2022-31.5%-47.4%
2023+6.1%+31.9%
2024-21.8%-28.4%
2025-18.5%-55.1%
2026-9.0%-48.3%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are MKTX and MYGN good diversifiers for each other?

Yes: at -0.29, the two have gone their own ways historically, which is what genuine diversification looks like.

FAQ

What is the correlation between MKTX and MYGN?

Using weekly returns as of 2026-08-27: -0.29 over 3 years, with -0.61 over the last year and -0.02 over 5 years.

Is MYGN a good diversifier for MKTX?

Yes: at -0.29, the two have gone their own ways historically, which is what genuine diversification looks like.

What does a correlation of -0.29 mean?

A reading of -0.29 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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MKTX vs MYGN: 3-year weekly correlation -0.29MKTX vs MYGN-0.29

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Related comparisons

Hubs: MKTX correlations · MYGN correlations