LXRX vs QQQ: Correlation
How closely do Lexicon Pharmaceuticals, Inc. (LXRX) and Invesco QQQ Trust (QQQ) trade together? Their weekly returns over three years give a correlation of 0.22, which is weak.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are LXRX and QQQ?
On 3 years of weekly data the LXRX/QQQ correlation comes out at 0.22, weak. The link has loosened recently: the 1-year correlation (0.09) runs below the 3-year figure (0.22). The 5-year figure is 0.29, and annualized covariance runs at 453.4 %².
Out of 11 assets tracked against LXRX, QQQ lands near the bottom at #8. Correlation aside, the last 12 months split them widely, with LXRX ahead by 79.0 points (+105.3% versus +26.3%). One caveat on sizing: LXRX is 5.4 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
LXRX vs QQQ: side by side
| LXRX (Lexicon Pharmaceuticals, Inc.) | QQQ (Invesco QQQ Trust) | |
|---|---|---|
| 1-year return | +105.3% | +26.3% |
| 5-year return | -48.7% | +95.4% |
| Volatility (ann.) | 105.2% | 19.6% |
| Beta vs S&P 500 | 1.98 | 1.28 |
| Max drawdown (3Y) | -91.9% | -22.8% |
| Market cap | $1.0B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.44% |
| Expense ratio | – | 0.18% |
| Assets under management | – | $452.8B |
| Sector / category | US Listed | ETF · US Growth & Tech |
QQQ is a Large Growth fund from Invesco: $452.8B under management, 104 holdings, a 0.18% expense ratio, a 0.44% trailing dividend yield.
Year-by-year returns
| Year | LXRX | QQQ |
|---|---|---|
| 2022 | -51.5% | -32.6% |
| 2023 | -19.9% | +54.9% |
| 2024 | -51.6% | +25.6% |
| 2025 | +55.4% | +20.8% |
| 2026 | +101.7% | +17.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are LXRX and QQQ good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.22 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between LXRX and QQQ?
Using weekly returns as of 2026-08-27: 0.22 over 3 years, with 0.09 over the last year and 0.29 over 5 years.
Is QQQ a good diversifier for LXRX?
Yes, to a useful degree: a correlation of 0.22 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.22 mean?
On the −1 to +1 scale, 0.22 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/lxrx-vs-qqq.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/lxrx-vs-qqq/)
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Related comparisons
Hubs: LXRX correlations · QQQ correlations
