LSTA vs SPY: Correlation
How closely do Lisata Therapeutics, Inc. (LSTA) and SPDR S&P 500 ETF Trust (SPY) trade together? Their weekly returns over three years give a correlation of 0.05, which is near-zero.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are LSTA and SPY?
On 3 years of weekly data the LSTA/SPY correlation comes out at 0.05, near zero, meaning they move largely independently. The past 12 months show a weaker link (-0.11) than the 3-year average (0.05). The 5-year figure is 0.15, and annualized covariance runs at 64.9 %².
Within LSTA's tracked universe of 15 assets, SPY comes in at #8 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months SPY outperformed by 47.8 percentage points (-27.2% for LSTA against +20.6% for SPY). One caveat on sizing: LSTA is 6.3 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
LSTA vs SPY: side by side
| LSTA (Lisata Therapeutics, Inc.) | SPY (SPDR S&P 500 ETF Trust) | |
|---|---|---|
| 1-year return | -27.2% | +20.6% |
| 5-year return | -90.4% | +82.4% |
| Volatility (ann.) | 91.1% | 14.5% |
| Beta vs S&P 500 | 0.31 | 1.00 |
| Max drawdown (3Y) | -80.4% | -18.8% |
| Market cap | – | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.01% |
| Expense ratio | – | 0.09% |
| Assets under management | – | $795.3B |
| Sector / category | US Listed | ETF · US Large Cap |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | LSTA | SPY |
|---|---|---|
| 2022 | -79.9% | -18.2% |
| 2023 | +7.9% | +26.2% |
| 2024 | +9.2% | +24.9% |
| 2025 | -37.6% | +17.7% |
| 2026 | -2.2% | +13.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are LSTA and SPY good diversifiers for each other?
Yes. With a correlation of 0.05, LSTA and SPY have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
FAQ
What is the correlation between LSTA and SPY?
The LSTA/SPY correlation stands at 0.05 on a 3-year window (1 year: -0.11, 5 years: 0.15), computed from weekly returns as of 2026-08-27.
Is SPY a good diversifier for LSTA?
Yes. With a correlation of 0.05, LSTA and SPY have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
What does a correlation of 0.05 mean?
On the −1 to +1 scale, 0.05 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
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Related comparisons
Hubs: LSTA correlations · SPY correlations
