LENZ vs SPY: Correlation
Measured on weekly returns over the past three years, LENZ Therapeutics, Inc. (LENZ) and SPDR S&P 500 ETF Trust (SPY) carry a correlation of 0.23, a weak link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are LENZ and SPY?
On 3 years of weekly data the LENZ/SPY correlation comes out at 0.23, weak. Little has changed lately, as the 1-year reading of 0.31 lands near the 3-year figure. The 5-year figure is 0.23, and annualized covariance runs at 263.7 %².
Out of 10 assets tracked against LENZ, SPY lands near the bottom at #6. Their recent paths diverged sharply: over the last 12 months SPY outperformed by 107.7 percentage points (-87.1% for LENZ against +20.6% for SPY). Note the risk asymmetry: LENZ runs 5.4 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
LENZ vs SPY: side by side
| LENZ (LENZ Therapeutics, Inc.) | SPY (SPDR S&P 500 ETF Trust) | |
|---|---|---|
| 1-year return | -87.1% | +20.6% |
| 5-year return | -92.9% | +82.4% |
| Volatility (ann.) | 78.6% | 14.5% |
| Beta vs S&P 500 | 1.26 | 1.00 |
| Max drawdown (3Y) | -90.6% | -18.8% |
| Market cap | $0.2B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.01% |
| Expense ratio | – | 0.09% |
| Assets under management | – | $795.3B |
| Sector / category | US Listed | ETF · US Large Cap |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | LENZ | SPY |
|---|---|---|
| 2022 | -73.3% | -18.2% |
| 2023 | -21.1% | +26.2% |
| 2024 | +230.7% | +24.9% |
| 2025 | -44.6% | +17.7% |
| 2026 | -69.9% | +13.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are LENZ and SPY good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.23 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between LENZ and SPY?
Using weekly returns as of 2026-08-27: 0.23 over 3 years, with 0.31 over the last year and 0.23 over 5 years.
Is SPY a good diversifier for LENZ?
Yes, to a useful degree: a correlation of 0.23 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.23 mean?
On the −1 to +1 scale, 0.23 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
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Related comparisons
Hubs: LENZ correlations · SPY correlations
