KPTI vs MBAI: Correlation
How closely do Karyopharm Therapeutics Inc. (KPTI) and Check-Cap Ltd. (MBAI) trade together? Their weekly returns over three years give a correlation of -0.32, which is negative.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are KPTI and MBAI?
Across a 3-year window, the weekly returns of KPTI and MBAI correlate at -0.32, negative, meaning they tend to move in opposite directions. The past 12 months show a weaker link (-0.53) than the 3-year average (-0.32). Stretching to 5 years gives -0.22, with an annualized covariance of -15104.0 %².
Among the 18 assets we track against KPTI, MBAI ranks #8 by 3-year correlation. The last year tells two different stories: MBAI led by 986.0 percentage points, -75.2% for KPTI against +910.8% for MBAI. Note the risk asymmetry: MBAI runs 4.8 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
KPTI vs MBAI: side by side
| KPTI (Karyopharm Therapeutics Inc.) | MBAI (Check-Cap Ltd.) | |
|---|---|---|
| 1-year return | -75.2% | +910.8% |
| 5-year return | -97.6% | -69.3% |
| Volatility (ann.) | 98.0% | 474.4% |
| Beta vs S&P 500 | 1.63 | 1.76 |
| Max drawdown (3Y) | -92.7% | -87.3% |
| Market cap | – | – |
| P/E (trailing) | – | 1.4 |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | KPTI | MBAI |
|---|---|---|
| 2022 | -47.1% | -83.7% |
| 2023 | -74.6% | -5.5% |
| 2024 | -21.8% | -52.4% |
| 2025 | -27.4% | +63.6% |
| 2026 | -73.6% | +305.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are KPTI and MBAI good diversifiers for each other?
Yes: at -0.32, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between KPTI and MBAI?
Using weekly returns as of 2026-08-27: -0.32 over 3 years, with -0.53 over the last year and -0.22 over 5 years.
Is MBAI a good diversifier for KPTI?
Yes: at -0.32, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.32 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
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Hubs: KPTI correlations · MBAI correlations
