ISRG vs NXTC: Correlation
Measured on weekly returns over the past three years, Intuitive Surgical (ISRG) and NextCure, Inc. (NXTC) carry a correlation of -0.19, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ISRG and NXTC?
On 3 years of weekly data the ISRG/NXTC correlation comes out at -0.19, negative, meaning they tend to move in opposite directions. The relationship has been stable: the 1-year correlation (-0.27) sits close to the 3-year figure. The 5-year figure is -0.09, and annualized covariance runs at -945.8 %².
Among the 36 assets we track against ISRG, NXTC ranks #31 by 3-year correlation. Correlation aside, the last 12 months split them widely, with NXTC ahead by 37.4 points (-22.1% versus +15.3%). Risk is not evenly split, since NXTC carries 5.1 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ISRG vs NXTC: side by side
| ISRG (Intuitive Surgical) | NXTC (NextCure, Inc.) | |
|---|---|---|
| 1-year return | -22.1% | +15.3% |
| 5-year return | +4.0% | -93.2% |
| Volatility (ann.) | 31.1% | 160.1% |
| Beta vs S&P 500 | 1.20 | 1.18 |
| Max drawdown (3Y) | -45.6% | -94.6% |
| Market cap | $131.5B | – |
| P/E (trailing) | 42.5 | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | Health Care | US Listed |
Year-by-year returns
| Year | ISRG | NXTC |
|---|---|---|
| 2022 | -26.1% | -76.5% |
| 2023 | +27.1% | -19.1% |
| 2024 | +54.7% | -32.4% |
| 2025 | +8.5% | +53.4% |
| 2026 | -35.2% | -57.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ISRG and NXTC good diversifiers for each other?
By historical standards, yes. A correlation of -0.19 means the two rarely move for the same reasons.
FAQ
What is the correlation between ISRG and NXTC?
As of 2026-08-27, the correlation of weekly returns between ISRG and NXTC is -0.19 over 3 years, -0.27 over 1 year and -0.09 over 5 years.
Is NXTC a good diversifier for ISRG?
By historical standards, yes. A correlation of -0.19 means the two rarely move for the same reasons.
What does a correlation of -0.19 mean?
On the −1 to +1 scale, -0.19 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/isrg-vs-nxtc.json
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[](https://www.pairbook.io/pair/isrg-vs-nxtc/)
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Related comparisons
Hubs: ISRG correlations · NXTC correlations
