ISRG vs NERV: Correlation
How closely do Intuitive Surgical (ISRG) and Minerva Neurosciences, Inc (NERV) trade together? Their weekly returns over three years give a correlation of 0.43, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ISRG and NERV?
On 3 years of weekly data the ISRG/NERV correlation comes out at 0.43, moderate. Lately the two have moved closer together, with the 1-year correlation at 0.61 versus 0.43 over 3 years. The 5-year figure is 0.12, and annualized covariance runs at 1330.8 %².
Within ISRG's tracked universe of 36 assets, NERV comes in at #21 by 3-year correlation. Correlation aside, the last 12 months split them widely, with NERV ahead by 138.6 points (-22.1% versus +116.5%). Risk is not evenly split, since NERV carries 3.2 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ISRG vs NERV: side by side
| ISRG (Intuitive Surgical) | NERV (Minerva Neurosciences, Inc) | |
|---|---|---|
| 1-year return | -22.1% | +116.5% |
| 5-year return | +4.0% | -63.8% |
| Volatility (ann.) | 31.1% | 99.2% |
| Beta vs S&P 500 | 1.20 | 1.61 |
| Max drawdown (3Y) | -45.6% | -89.3% |
| Market cap | $131.5B | $0.2B |
| P/E (trailing) | 42.5 | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | Health Care | US Listed |
Year-by-year returns
| Year | ISRG | NERV |
|---|---|---|
| 2022 | -26.1% | -75.2% |
| 2023 | +27.1% | +286.8% |
| 2024 | +54.7% | -63.9% |
| 2025 | +8.5% | +80.9% |
| 2026 | -35.2% | +27.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ISRG and NERV good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.43 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between ISRG and NERV?
The ISRG/NERV correlation stands at 0.43 on a 3-year window (1 year: 0.61, 5 years: 0.12), computed from weekly returns as of 2026-08-27.
Is NERV a good diversifier for ISRG?
Yes, to a useful degree: a correlation of 0.43 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.43 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/isrg-vs-nerv.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/isrg-vs-nerv/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: ISRG correlations · NERV correlations
