INAB vs SPY: Correlation
How closely do IN8bio, Inc. (INAB) and SPDR S&P 500 ETF Trust (SPY) trade together? Their weekly returns over three years give a correlation of 0.21, which is weak.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are INAB and SPY?
Over the past 3 years, INAB and SPY moved with a correlation of 0.21, which is weak. The relationship has been stable: the 1-year correlation (0.21) sits close to the 3-year figure. Over 5 years the correlation is 0.20, and the annualized covariance of weekly returns is 348.4 %².
SPY is close to the least connected end of INAB's tracked universe, ranking #9 of 12. The last year tells two different stories: SPY led by 75.0 percentage points, -54.4% for INAB against +20.6% for SPY. Note the risk asymmetry: INAB runs 7.8 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
INAB vs SPY: side by side
| INAB (IN8bio, Inc.) | SPY (SPDR S&P 500 ETF Trust) | |
|---|---|---|
| 1-year return | -54.4% | +20.6% |
| 5-year return | -99.5% | +82.4% |
| Volatility (ann.) | 113.3% | 14.5% |
| Beta vs S&P 500 | 1.67 | 1.00 |
| Max drawdown (3Y) | -98.6% | -18.8% |
| Market cap | – | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 1.01% |
| Expense ratio | – | 0.09% |
| Assets under management | – | $795.3B |
| Sector / category | US Listed | ETF · US Large Cap |
SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.
Year-by-year returns
| Year | INAB | SPY |
|---|---|---|
| 2022 | -47.4% | -18.2% |
| 2023 | -40.3% | +26.2% |
| 2024 | -81.4% | +24.9% |
| 2025 | -69.6% | +17.7% |
| 2026 | -55.6% | +13.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are INAB and SPY good diversifiers for each other?
Reasonably. At 0.21, INAB and SPY keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between INAB and SPY?
As of 2026-08-27, the correlation of weekly returns between INAB and SPY is 0.21 over 3 years, 0.21 over 1 year and 0.20 over 5 years.
Is SPY a good diversifier for INAB?
Reasonably. At 0.21, INAB and SPY keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.21 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
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Related comparisons
Hubs: INAB correlations · SPY correlations
