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IMRX vs VXZ: Correlation

How closely do Immuneering Corporation (IMRX) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) trade together? Their weekly returns over three years give a correlation of -0.27, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.27
negative
Correlation (1Y)
-0.12
last 12 months
Correlation (5Y)
-0.20
long-run
Ann. covariance
-800.2
%² · weekly, annualized

How correlated are IMRX and VXZ?

On 3 years of weekly data the IMRX/VXZ correlation comes out at -0.27, negative, meaning they tend to move in opposite directions. The link has tightened recently: the 1-year correlation (-0.12) runs above the 3-year figure (-0.27). The 5-year figure is -0.20, and annualized covariance runs at -800.2 %².

Out of 11 assets tracked against IMRX, VXZ lands near the bottom at #11. Correlation aside, the last 12 months split them widely, with IMRX ahead by 16.5 points (+0.4% versus -16.1%). Note the risk asymmetry: IMRX runs 4.5 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

IMRX vs VXZ: side by side

IMRX (Immuneering Corporation)VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN)
1-year return+0.4%-16.1%
5-year return-80.2%-53.1%
Volatility (ann.)116.1%25.6%
Beta vs S&P 5002.14-1.31
Max drawdown (3Y)-88.7%-36.4%
Market cap$0.3B
P/E (trailing)
Dividend yield0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: VXZ -36.4% vs -88.7%Higher 5y return: VXZ -53.1% vs -80.2%
-25%0%+68%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. IMRX · VXZ

Year-by-year returns

YearIMRXVXZ
2022-70.0%+0.5%
2023+51.5%-44.0%
2024-70.1%-12.7%
2025+199.1%+5.7%
2026-20.8%-10.5%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are IMRX and VXZ good diversifiers for each other?

Yes: at -0.27, the two have gone their own ways historically, which is what genuine diversification looks like.

FAQ

What is the correlation between IMRX and VXZ?

The IMRX/VXZ correlation stands at -0.27 on a 3-year window (1 year: -0.12, 5 years: -0.20), computed from weekly returns as of 2026-08-27.

Is VXZ a good diversifier for IMRX?

Yes: at -0.27, the two have gone their own ways historically, which is what genuine diversification looks like.

What does a correlation of -0.27 mean?

On the −1 to +1 scale, -0.27 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/imrx-vs-vxz.json

IMRX vs VXZ: 3-year weekly correlation -0.27IMRX vs VXZ-0.27

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Related comparisons

Hubs: IMRX correlations · VXZ correlations