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HALO vs SPY: Correlation

How closely do Halozyme Therapeutics, Inc. (HALO) and SPDR S&P 500 ETF Trust (SPY) trade together? Their weekly returns over three years give a correlation of 0.19, which is weak.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.19
weak
Correlation (1Y)
0.17
last 12 months
Correlation (5Y)
0.28
long-run
Ann. covariance
113.7
%² · weekly, annualized

How correlated are HALO and SPY?

Over the past 3 years, HALO and SPY moved with a correlation of 0.19, which is weak. Little has changed lately, as the 1-year reading of 0.17 lands near the 3-year figure. Over 5 years the correlation is 0.28, and the annualized covariance of weekly returns is 113.7 %².

Among the 12 assets we track against HALO, SPY ranks #6 by 3-year correlation. The last year tells two different stories: HALO led by 25.5 percentage points, +46.1% for HALO against +20.6% for SPY. Note the risk asymmetry: HALO runs 2.9 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

HALO vs SPY: side by side

HALO (Halozyme Therapeutics, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return+46.1%+20.6%
5-year return+154.8%+82.4%
Volatility (ann.)41.5%14.5%
Beta vs S&P 5000.541.00
Max drawdown (3Y)-33.9%-18.8%
Market cap$12.1B
P/E (trailing)31.4
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -33.9%Higher 5y return: HALO +154.8% vs +82.4%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-18%0%+44%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. HALO · SPY

Year-by-year returns

YearHALOSPY
2022+41.5%-18.2%
2023-35.0%+26.2%
2024+29.4%+24.9%
2025+40.8%+17.7%
2026+58.9%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are HALO and SPY good diversifiers for each other?

By historical standards, yes. A correlation of 0.19 means the two rarely move for the same reasons.

FAQ

What is the correlation between HALO and SPY?

The HALO/SPY correlation stands at 0.19 on a 3-year window (1 year: 0.17, 5 years: 0.28), computed from weekly returns as of 2026-08-27.

Is SPY a good diversifier for HALO?

By historical standards, yes. A correlation of 0.19 means the two rarely move for the same reasons.

What does a correlation of 0.19 mean?

A reading of 0.19 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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HALO vs SPY: 3-year weekly correlation 0.19HALO vs SPY0.19

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Hubs: HALO correlations · SPY correlations