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GNPX vs SPY: Correlation

Genprex, Inc. (GNPX) and SPDR S&P 500 ETF Trust (SPY) show a near-zero relationship: their 3-year correlation of weekly returns is -0.03.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.03
near-zero
Correlation (1Y)
0.10
last 12 months
Correlation (5Y)
0.04
long-run
Ann. covariance
-95.0
%² · weekly, annualized

How correlated are GNPX and SPY?

Over the past 3 years, GNPX and SPY moved with a correlation of -0.03, which is near zero, meaning they move largely independently. The link has tightened recently: the 1-year correlation (0.10) runs above the 3-year figure (-0.03). Over 5 years the correlation is 0.04, and the annualized covariance of weekly returns is -95.0 %².

By 3-year correlation, SPY places #7 of the 33 assets tracked against GNPX. Correlation aside, the last 12 months split them widely, with SPY ahead by 118.7 points (-98.1% versus +20.6%). One caveat on sizing: GNPX is 17.6 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

GNPX vs SPY: side by side

GNPX (Genprex, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return-98.1%+20.6%
5-year return-100.0%+82.4%
Volatility (ann.)255.0%14.5%
Beta vs S&P 500-0.451.00
Max drawdown (3Y)-100.0%-18.8%
Market cap
P/E (trailing)0.1
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -100.0%Higher 5y return: SPY +82.4% vs -100.0%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-99%0%+58%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. GNPX · SPY

Year-by-year returns

YearGNPXSPY
2022+10.7%-18.2%
2023-84.1%+26.2%
2024-90.7%+24.9%
2025-95.9%+17.7%
2026-90.6%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are GNPX and SPY good diversifiers for each other?

By historical standards, yes. A correlation of -0.03 means the two rarely move for the same reasons.

FAQ

What is the correlation between GNPX and SPY?

As of 2026-08-27, the correlation of weekly returns between GNPX and SPY is -0.03 over 3 years, 0.10 over 1 year and 0.04 over 5 years.

Is SPY a good diversifier for GNPX?

By historical standards, yes. A correlation of -0.03 means the two rarely move for the same reasons.

What does a correlation of -0.03 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

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GNPX vs SPY: 3-year weekly correlation -0.03GNPX vs SPY-0.03

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Hubs: GNPX correlations · SPY correlations