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GLMD vs KPTI: Correlation

Galmed Pharmaceuticals Ltd. (GLMD) and Karyopharm Therapeutics Inc. (KPTI) show a negative relationship: their 3-year correlation of weekly returns is -0.36.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.36
negative
Correlation (1Y)
-0.53
last 12 months
Correlation (5Y)
-0.27
long-run
Ann. covariance
-21713.5
%² · weekly, annualized

How correlated are GLMD and KPTI?

Across a 3-year window, the weekly returns of GLMD and KPTI correlate at -0.36, negative, meaning they tend to move in opposite directions. The past 12 months show a weaker link (-0.53) than the 3-year average (-0.36). Stretching to 5 years gives -0.27, with an annualized covariance of -21713.5 %².

Among the 10 assets we track against GLMD, KPTI sits near the bottom by co-movement, at rank #8. Their recent paths diverged sharply: over the last 12 months GLMD outperformed by 285.0 percentage points (+209.8% for GLMD against -75.2% for KPTI). Note the risk asymmetry: GLMD runs 6.3 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

GLMD vs KPTI: side by side

GLMD (Galmed Pharmaceuticals Ltd.)KPTI (Karyopharm Therapeutics Inc.)
1-year return+209.8%-75.2%
5-year return-99.3%-97.6%
Volatility (ann.)619.4%98.0%
Beta vs S&P 5002.451.63
Max drawdown (3Y)-96.9%-92.7%
Market cap
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: KPTI -92.7% vs -96.9%Higher 5y return: KPTI -97.6% vs -99.3%
-71%0%+265%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. GLMD · KPTI

Year-by-year returns

YearGLMDKPTI
2022-72.5%-47.1%
2023-93.9%-74.6%
2024-41.6%-21.8%
2025-76.5%-27.4%
2026+473.3%-73.6%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are GLMD and KPTI good diversifiers for each other?

Yes: at -0.36, the two have gone their own ways historically, which is what genuine diversification looks like.

FAQ

What is the correlation between GLMD and KPTI?

As of 2026-08-27, the correlation of weekly returns between GLMD and KPTI is -0.36 over 3 years, -0.53 over 1 year and -0.27 over 5 years.

Is KPTI a good diversifier for GLMD?

Yes: at -0.36, the two have gone their own ways historically, which is what genuine diversification looks like.

What does a correlation of -0.36 mean?

A reading of -0.36 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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GLMD vs KPTI: 3-year weekly correlation -0.36GLMD vs KPTI-0.36

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Hubs: GLMD correlations · KPTI correlations