GLMD vs KPTI: Correlation
Galmed Pharmaceuticals Ltd. (GLMD) and Karyopharm Therapeutics Inc. (KPTI) show a negative relationship: their 3-year correlation of weekly returns is -0.36.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are GLMD and KPTI?
Across a 3-year window, the weekly returns of GLMD and KPTI correlate at -0.36, negative, meaning they tend to move in opposite directions. The past 12 months show a weaker link (-0.53) than the 3-year average (-0.36). Stretching to 5 years gives -0.27, with an annualized covariance of -21713.5 %².
Among the 10 assets we track against GLMD, KPTI sits near the bottom by co-movement, at rank #8. Their recent paths diverged sharply: over the last 12 months GLMD outperformed by 285.0 percentage points (+209.8% for GLMD against -75.2% for KPTI). Note the risk asymmetry: GLMD runs 6.3 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
GLMD vs KPTI: side by side
| GLMD (Galmed Pharmaceuticals Ltd.) | KPTI (Karyopharm Therapeutics Inc.) | |
|---|---|---|
| 1-year return | +209.8% | -75.2% |
| 5-year return | -99.3% | -97.6% |
| Volatility (ann.) | 619.4% | 98.0% |
| Beta vs S&P 500 | 2.45 | 1.63 |
| Max drawdown (3Y) | -96.9% | -92.7% |
| Market cap | – | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | GLMD | KPTI |
|---|---|---|
| 2022 | -72.5% | -47.1% |
| 2023 | -93.9% | -74.6% |
| 2024 | -41.6% | -21.8% |
| 2025 | -76.5% | -27.4% |
| 2026 | +473.3% | -73.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are GLMD and KPTI good diversifiers for each other?
Yes: at -0.36, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between GLMD and KPTI?
As of 2026-08-27, the correlation of weekly returns between GLMD and KPTI is -0.36 over 3 years, -0.53 over 1 year and -0.27 over 5 years.
Is KPTI a good diversifier for GLMD?
Yes: at -0.36, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.36 mean?
A reading of -0.36 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/glmd-vs-kpti.json
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[](https://www.pairbook.io/pair/glmd-vs-kpti/)
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Hubs: GLMD correlations · KPTI correlations