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GANX vs SPY: Correlation

Measured on weekly returns over the past three years, Gain Therapeutics, Inc. (GANX) and SPDR S&P 500 ETF Trust (SPY) carry a correlation of 0.24, a weak link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.24
weak
Correlation (1Y)
0.23
last 12 months
Correlation (5Y)
0.25
long-run
Ann. covariance
335.9
%² · weekly, annualized

How correlated are GANX and SPY?

On 3 years of weekly data the GANX/SPY correlation comes out at 0.24, weak. Little has changed lately, as the 1-year reading of 0.23 lands near the 3-year figure. The 5-year figure is 0.25, and annualized covariance runs at 335.9 %².

Out of 10 assets tracked against GANX, SPY lands near the bottom at #6. The last year tells two different stories: SPY led by 21.1 percentage points, -0.5% for GANX against +20.6% for SPY. Risk is not evenly split, since GANX carries 6.8 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

GANX vs SPY: side by side

GANX (Gain Therapeutics, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return-0.5%+20.6%
5-year return-76.4%+82.4%
Volatility (ann.)98.1%14.5%
Beta vs S&P 5001.611.00
Max drawdown (3Y)-81.4%-18.8%
Market cap$0.1B
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -81.4%Higher 5y return: SPY +82.4% vs -76.4%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-10%0%+135%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. GANX · SPY

Year-by-year returns

YearGANXSPY
2022-42.4%-18.2%
2023+4.3%+26.2%
2024-33.8%+24.9%
2025+49.1%+17.7%
2026-42.5%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are GANX and SPY good diversifiers for each other?

Reasonably. At 0.24, GANX and SPY keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

FAQ

What is the correlation between GANX and SPY?

Using weekly returns as of 2026-08-27: 0.24 over 3 years, with 0.23 over the last year and 0.25 over 5 years.

Is SPY a good diversifier for GANX?

Reasonably. At 0.24, GANX and SPY keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.

What does a correlation of 0.24 mean?

On the −1 to +1 scale, 0.24 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

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GANX vs SPY: 3-year weekly correlation 0.24GANX vs SPY0.24

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Hubs: GANX correlations · SPY correlations