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EXEL vs SPY: Correlation

How closely do Exelixis, Inc. (EXEL) and SPDR S&P 500 ETF Trust (SPY) trade together? Their weekly returns over three years give a correlation of 0.32, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.32
moderate
Correlation (1Y)
0.20
last 12 months
Correlation (5Y)
0.34
long-run
Ann. covariance
163.4
%² · weekly, annualized

How correlated are EXEL and SPY?

Over the past 3 years, EXEL and SPY moved with a correlation of 0.32, which is moderate. The link has loosened recently: the 1-year correlation (0.20) runs below the 3-year figure (0.32). Over 5 years the correlation is 0.34, and the annualized covariance of weekly returns is 163.4 %².

By 3-year correlation, SPY places #6 of the 11 assets tracked against EXEL. Correlation aside, the last 12 months split them widely, with EXEL ahead by 22.9 points (+43.5% versus +20.6%). Risk is not evenly split, since EXEL carries 2.4 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

EXEL vs SPY: side by side

EXEL (Exelixis, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return+43.5%+20.6%
5-year return+186.9%+82.4%
Volatility (ann.)34.8%14.5%
Beta vs S&P 5000.781.00
Max drawdown (3Y)-25.3%-18.8%
Market cap$13.7B
P/E (trailing)17.7
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -25.3%Higher 5y return: EXEL +186.9% vs +82.4%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-1%0%+49%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. EXEL · SPY

Year-by-year returns

YearEXELSPY
2022-12.3%-18.2%
2023+49.6%+26.2%
2024+38.8%+24.9%
2025+31.6%+17.7%
2026+26.1%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are EXEL and SPY good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.32 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between EXEL and SPY?

Using weekly returns as of 2026-08-27: 0.32 over 3 years, with 0.20 over the last year and 0.34 over 5 years.

Is SPY a good diversifier for EXEL?

Yes, to a useful degree: a correlation of 0.32 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.32 mean?

A reading of 0.32 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

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EXEL vs SPY: 3-year weekly correlation 0.32EXEL vs SPY0.32

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Related comparisons

Hubs: EXEL correlations · SPY correlations