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DRMA vs SPY: Correlation

Measured on weekly returns over the past three years, Dermata Therapeutics, Inc. (DRMA) and SPDR S&P 500 ETF Trust (SPY) carry a correlation of 0.20, a weak link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.20
weak
Correlation (1Y)
0.24
last 12 months
Correlation (5Y)
0.17
long-run
Ann. covariance
256.2
%² · weekly, annualized

How correlated are DRMA and SPY?

On 3 years of weekly data the DRMA/SPY correlation comes out at 0.20, weak. Little has changed lately, as the 1-year reading of 0.24 lands near the 3-year figure. The 5-year figure is 0.17, and annualized covariance runs at 256.2 %².

SPY is close to the least connected end of DRMA's tracked universe, ranking #9 of 13. The last year tells two different stories: SPY led by 93.0 percentage points, -72.4% for DRMA against +20.6% for SPY. One caveat on sizing: DRMA is 6.2 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

DRMA vs SPY: side by side

DRMA (Dermata Therapeutics, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return-72.4%+20.6%
5-year return-100.0%+82.4%
Volatility (ann.)90.1%14.5%
Beta vs S&P 5001.231.00
Max drawdown (3Y)-99.4%-18.8%
Market cap
P/E (trailing)
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -99.4%Higher 5y return: SPY +82.4% vs -100.0%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-79%0%+21%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. DRMA · SPY

Year-by-year returns

YearDRMASPY
2022-76.5%-18.2%
2023-90.7%+26.2%
2024-85.2%+24.9%
2025-82.8%+17.7%
2026-37.1%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are DRMA and SPY good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.20 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between DRMA and SPY?

Using weekly returns as of 2026-08-27: 0.20 over 3 years, with 0.24 over the last year and 0.17 over 5 years.

Is SPY a good diversifier for DRMA?

Yes, to a useful degree: a correlation of 0.20 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.20 mean?

On the −1 to +1 scale, 0.20 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

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DRMA vs SPY: 3-year weekly correlation 0.20DRMA vs SPY0.20

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Hubs: DRMA correlations · SPY correlations