DNLI vs SNDX: Correlation
How closely do Denali Therapeutics Inc. (DNLI) and Syndax Pharmaceuticals, Inc. (SNDX) trade together? Their weekly returns over three years give a correlation of 0.55, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are DNLI and SNDX?
On 3 years of weekly data the DNLI/SNDX correlation comes out at 0.55, moderate. The link has loosened recently: the 1-year correlation (0.45) runs below the 3-year figure (0.55). The 5-year figure is 0.51, and annualized covariance runs at 1917.0 %².
By 3-year correlation, SNDX places #8 of the 25 assets tracked against DNLI. Correlation aside, the last 12 months split them widely, with DNLI ahead by 34.1 points (+58.1% versus +24.0%).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
DNLI vs SNDX: side by side
| DNLI (Denali Therapeutics Inc.) | SNDX (Syndax Pharmaceuticals, Inc.) | |
|---|---|---|
| 1-year return | +58.1% | +24.0% |
| 5-year return | -53.4% | +16.9% |
| Volatility (ann.) | 60.6% | 57.8% |
| Beta vs S&P 500 | 2.02 | 1.25 |
| Max drawdown (3Y) | -63.7% | -64.8% |
| Market cap | $3.9B | $1.8B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | DNLI | SNDX |
|---|---|---|
| 2022 | -37.6% | +16.3% |
| 2023 | -22.8% | -15.1% |
| 2024 | -5.0% | -38.8% |
| 2025 | -19.0% | +58.9% |
| 2026 | +49.4% | -4.0% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are DNLI and SNDX good diversifiers for each other?
To a limited degree. At 0.55 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.
FAQ
What is the correlation between DNLI and SNDX?
Using weekly returns as of 2026-08-27: 0.55 over 3 years, with 0.45 over the last year and 0.51 over 5 years.
Is SNDX a good diversifier for DNLI?
To a limited degree. At 0.55 the two still catch most of the same waves, so the pair smooths returns a little without insulating either from a shared selloff.
What does a correlation of 0.55 mean?
A reading of 0.55 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/dnli-vs-sndx.json
Embed this badge (it refreshes with the data), with attribution:
[](https://www.pairbook.io/pair/dnli-vs-sndx/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: DNLI correlations · SNDX correlations
