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DNLI vs RARE: Correlation

How closely do Denali Therapeutics Inc. (DNLI) and Ultragenyx Pharmaceutical Inc. (RARE) trade together? Their weekly returns over three years give a correlation of 0.55, which is moderate.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.55
moderate
Correlation (1Y)
0.66
last 12 months
Correlation (5Y)
0.52
long-run
Ann. covariance
1713.4
%² · weekly, annualized

How correlated are DNLI and RARE?

On 3 years of weekly data the DNLI/RARE correlation comes out at 0.55, moderate. The link has tightened recently: the 1-year correlation (0.66) runs above the 3-year figure (0.55). The 5-year figure is 0.52, and annualized covariance runs at 1713.4 %².

By 3-year correlation, RARE places #7 of the 25 assets tracked against DNLI. Correlation aside, the last 12 months split them widely, with DNLI ahead by 70.8 points (+58.1% versus -12.7%).

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

DNLI vs RARE: side by side

DNLI (Denali Therapeutics Inc.)RARE (Ultragenyx Pharmaceutical Inc.)
1-year return+58.1%-12.7%
5-year return-53.4%-72.6%
Volatility (ann.)60.6%51.1%
Beta vs S&P 5002.021.38
Max drawdown (3Y)-63.7%-68.8%
Market cap$3.9B$2.6B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: DNLI -63.7% vs -68.8%Higher 5y return: DNLI -53.4% vs -72.6%
-39%0%+67%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). DNLI · RARE

Year-by-year returns

YearDNLIRARE
2022-37.6%-44.9%
2023-22.8%+3.2%
2024-5.0%-12.0%
2025-19.0%-45.3%
2026+49.4%+14.2%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are DNLI and RARE good diversifiers for each other?

Only partially. A correlation of 0.55 means DNLI and RARE share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.

FAQ

What is the correlation between DNLI and RARE?

The DNLI/RARE correlation stands at 0.55 on a 3-year window (1 year: 0.66, 5 years: 0.52), computed from weekly returns as of 2026-08-27.

Is RARE a good diversifier for DNLI?

Only partially. A correlation of 0.55 means DNLI and RARE share most of their swings. Pairing them dampens volatility somewhat, but it will not protect against a common drawdown.

What does a correlation of 0.55 mean?

On the −1 to +1 scale, 0.55 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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$ curl https://www.pairbook.io/api/v1/pairs/dnli-vs-rare.json

DNLI vs RARE: 3-year weekly correlation 0.55DNLI vs RARE0.55

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Related comparisons

Hubs: DNLI correlations · RARE correlations