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DNLI vs QQQ: Correlation

Denali Therapeutics Inc. (DNLI) and Invesco QQQ Trust (QQQ) show a moderate relationship: their 3-year correlation of weekly returns is 0.45.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.45
moderate
Correlation (1Y)
0.36
last 12 months
Correlation (5Y)
0.46
long-run
Ann. covariance
539.1
%² · weekly, annualized

How correlated are DNLI and QQQ?

Across a 3-year window, the weekly returns of DNLI and QQQ correlate at 0.45, moderate. Recent behaviour matches the longer record: 0.36 over 1 year against 0.45 over 3. Stretching to 5 years gives 0.46, with an annualized covariance of 539.1 %².

Within DNLI's tracked universe of 25 assets, QQQ comes in at #17 by 3-year correlation. The last year tells two different stories: DNLI led by 31.8 percentage points, +58.1% for DNLI against +26.3% for QQQ. Risk is not evenly split, since DNLI carries 3.1 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

DNLI vs QQQ: side by side

DNLI (Denali Therapeutics Inc.)QQQ (Invesco QQQ Trust)
1-year return+58.1%+26.3%
5-year return-53.4%+95.4%
Volatility (ann.)60.6%19.6%
Beta vs S&P 5002.021.28
Max drawdown (3Y)-63.7%-22.8%
Market cap$3.9B
P/E (trailing)
Dividend yield0.00%0.44%
Expense ratio0.18%
Assets under management$452.8B
Sector / categoryUS ListedETF · US Growth & Tech
Higher yield: QQQ 0.44% vs 0.00%Smaller drawdown: QQQ -22.8% vs -63.7%Higher 5y return: QQQ +95.4% vs -53.4%

QQQ is a Large Growth fund from Invesco: $452.8B under management, 104 holdings, a 0.18% expense ratio, a 0.44% trailing dividend yield.

-17%0%+67%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. DNLI · QQQ

Year-by-year returns

YearDNLIQQQ
2022-37.6%-32.6%
2023-22.8%+54.9%
2024-5.0%+25.6%
2025-19.0%+20.8%
2026+49.4%+17.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are DNLI and QQQ good diversifiers for each other?

A fair diversifier. At 0.45, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

FAQ

What is the correlation between DNLI and QQQ?

Using weekly returns as of 2026-08-27: 0.45 over 3 years, with 0.36 over the last year and 0.46 over 5 years.

Is QQQ a good diversifier for DNLI?

A fair diversifier. At 0.45, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

What does a correlation of 0.45 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

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DNLI vs QQQ: 3-year weekly correlation 0.45DNLI vs QQQ0.45

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Hubs: DNLI correlations · QQQ correlations