DNLI vs PCVX: Correlation
How closely do Denali Therapeutics Inc. (DNLI) and Vaxcyte, Inc. (PCVX) trade together? Their weekly returns over three years give a correlation of 0.49, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are DNLI and PCVX?
Across a 3-year window, the weekly returns of DNLI and PCVX correlate at 0.49, moderate. The link has tightened recently: the 1-year correlation (0.61) runs above the 3-year figure (0.49). Stretching to 5 years gives 0.35, with an annualized covariance of 1719.8 %².
By 3-year correlation, PCVX places #12 of the 25 assets tracked against DNLI. The last year tells two different stories: PCVX led by 42.1 percentage points, +58.1% for DNLI against +100.2% for PCVX.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
DNLI vs PCVX: side by side
| DNLI (Denali Therapeutics Inc.) | PCVX (Vaxcyte, Inc.) | |
|---|---|---|
| 1-year return | +58.1% | +100.2% |
| 5-year return | -53.4% | +130.8% |
| Volatility (ann.) | 60.6% | 57.9% |
| Beta vs S&P 500 | 2.02 | 1.40 |
| Max drawdown (3Y) | -63.7% | -76.2% |
| Market cap | $3.9B | $9.1B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | DNLI | PCVX |
|---|---|---|
| 2022 | -37.6% | +101.6% |
| 2023 | -22.8% | +31.0% |
| 2024 | -5.0% | +30.4% |
| 2025 | -19.0% | -43.6% |
| 2026 | +49.4% | +32.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are DNLI and PCVX good diversifiers for each other?
A fair diversifier. At 0.49, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between DNLI and PCVX?
As of 2026-08-27, the correlation of weekly returns between DNLI and PCVX is 0.49 over 3 years, 0.61 over 1 year and 0.35 over 5 years.
Is PCVX a good diversifier for DNLI?
A fair diversifier. At 0.49, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.49 mean?
A reading of 0.49 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/dnli-vs-pcvx.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/dnli-vs-pcvx/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: DNLI correlations · PCVX correlations
