DMRA vs SPRB: Correlation
Measured on weekly returns over the past three years, Damora Therapeutics, Inc. (DMRA) and Spruce Biosciences, Inc. (SPRB) carry a correlation of 0.43, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are DMRA and SPRB?
On 3 years of weekly data the DMRA/SPRB correlation comes out at 0.43, moderate. The relationship has been stable: the 1-year correlation (0.43) sits close to the 3-year figure. The 5-year figure is 0.42, and annualized covariance runs at 142724.4 %².
Among the 16 assets we track against DMRA, SPRB ranks #4 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months DMRA outperformed by 64.4 percentage points (+810.7% for DMRA against +746.3% for SPRB). Risk is not evenly split, since SPRB carries 3.6 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
DMRA vs SPRB: side by side
| DMRA (Damora Therapeutics, Inc.) | SPRB (Spruce Biosciences, Inc.) | |
|---|---|---|
| 1-year return | +810.7% | +746.3% |
| 5-year return | -72.2% | -99.8% |
| Volatility (ann.) | 304.9% | 1086.4% |
| Beta vs S&P 500 | 0.22 | -7.82 |
| Max drawdown (3Y) | -90.0% | -100.0% |
| Market cap | $1.9B | $0.2B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | DMRA | SPRB |
|---|---|---|
| 2022 | -62.0% | -75.4% |
| 2023 | -37.4% | +167.1% |
| 2024 | -74.2% | -85.7% |
| 2025 | +394.8% | -96.3% |
| 2026 | +33.0% | -27.3% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are DMRA and SPRB good diversifiers for each other?
Reasonably. At 0.43, DMRA and SPRB keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between DMRA and SPRB?
As of 2026-08-27, the correlation of weekly returns between DMRA and SPRB is 0.43 over 3 years, 0.43 over 1 year and 0.42 over 5 years.
Is SPRB a good diversifier for DMRA?
Reasonably. At 0.43, DMRA and SPRB keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.43 mean?
A reading of 0.43 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
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Related comparisons
Hubs: DMRA correlations · SPRB correlations
