CUE vs HSIC: Correlation
Cue Biopharma, Inc. (CUE) and Henry Schein (HSIC) show a negative relationship: their 3-year correlation of weekly returns is -0.17.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CUE and HSIC?
On 3 years of weekly data the CUE/HSIC correlation comes out at -0.17, negative, meaning they tend to move in opposite directions. Little has changed lately, as the 1-year reading of -0.14 lands near the 3-year figure. The 5-year figure is -0.05, and annualized covariance runs at -652.6 %².
HSIC is close to the least connected end of CUE's tracked universe, ranking #11 of 15. Their recent paths diverged sharply: over the last 12 months HSIC outperformed by 17.3 percentage points (+13.6% for CUE against +30.9% for HSIC). Note the risk asymmetry: CUE runs 6.2 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CUE vs HSIC: side by side
| CUE (Cue Biopharma, Inc.) | HSIC (Henry Schein) | |
|---|---|---|
| 1-year return | +13.6% | +30.9% |
| 5-year return | -92.2% | +20.1% |
| Volatility (ann.) | 155.6% | 25.2% |
| Beta vs S&P 500 | 2.74 | 0.33 |
| Max drawdown (3Y) | -94.3% | -24.3% |
| Market cap | $0.2B | $10.1B |
| P/E (trailing) | – | 26.3 |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | Health Care |
Year-by-year returns
| Year | CUE | HSIC |
|---|---|---|
| 2022 | -74.8% | +3.0% |
| 2023 | -7.4% | -5.2% |
| 2024 | -58.7% | -8.6% |
| 2025 | -72.0% | +9.2% |
| 2026 | +207.8% | +19.4% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CUE and HSIC good diversifiers for each other?
Yes. With a correlation of -0.17, CUE and HSIC have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
FAQ
What is the correlation between CUE and HSIC?
As of 2026-08-27, the correlation of weekly returns between CUE and HSIC is -0.17 over 3 years, -0.14 over 1 year and -0.05 over 5 years.
Is HSIC a good diversifier for CUE?
Yes. With a correlation of -0.17, CUE and HSIC have moved largely independently, which makes them a genuinely diversifying pair by historical standards.
What does a correlation of -0.17 mean?
A reading of -0.17 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/cue-vs-hsic.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/cue-vs-hsic/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: CUE correlations · HSIC correlations
