CRVO vs OPRX: Correlation
CervoMed Inc. (CRVO) and OptimizeRx Corporation (OPRX) show a moderate relationship: their 3-year correlation of weekly returns is 0.39.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CRVO and OPRX?
Across a 3-year window, the weekly returns of CRVO and OPRX correlate at 0.39, moderate. The link has loosened recently: the 1-year correlation (0.10) runs below the 3-year figure (0.39). Stretching to 5 years gives 0.31, with an annualized covariance of 5815.1 %².
OPRX is one of the assets that tracks CRVO most closely: it ranks #3 out of the 17 assets we track against CRVO. The last year tells two different stories: OPRX led by 16.6 percentage points, -71.9% for CRVO against -55.3% for OPRX. Risk is not evenly split, since CRVO carries 2.1 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CRVO vs OPRX: side by side
| CRVO (CervoMed Inc.) | OPRX (OptimizeRx Corporation) | |
|---|---|---|
| 1-year return | -71.9% | -55.3% |
| 5-year return | -94.2% | -88.3% |
| Volatility (ann.) | 178.5% | 83.6% |
| Beta vs S&P 500 | 0.33 | 2.12 |
| Max drawdown (3Y) | -92.7% | -79.1% |
| Market cap | – | $0.1B |
| P/E (trailing) | – | 31.3 |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CRVO | OPRX |
|---|---|---|
| 2022 | -67.4% | -73.0% |
| 2023 | +0.5% | -14.8% |
| 2024 | -69.3% | -66.0% |
| 2025 | +237.6% | +152.3% |
| 2026 | -66.6% | -36.1% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CRVO and OPRX good diversifiers for each other?
Reasonably. At 0.39, CRVO and OPRX keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between CRVO and OPRX?
Using weekly returns as of 2026-08-27: 0.39 over 3 years, with 0.10 over the last year and 0.31 over 5 years.
Is OPRX a good diversifier for CRVO?
Reasonably. At 0.39, CRVO and OPRX keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.39 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/crvo-vs-oprx.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/crvo-vs-oprx/)
No key needed, free to use. Full endpoint list in the API documentation.
Related comparisons
Hubs: CRVO correlations · OPRX correlations
