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CRNX vs VXX: Correlation

Crinetics Pharmaceuticals, Inc. (CRNX) and iPath Series B S&P 500 VIX Short-Term Futures ETN (VXX) show a negative relationship: their 3-year correlation of weekly returns is -0.27.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.27
negative
Correlation (1Y)
-0.19
last 12 months
Correlation (5Y)
-0.25
long-run
Ann. covariance
-1481.6
%² · weekly, annualized

How correlated are CRNX and VXX?

On 3 years of weekly data the CRNX/VXX correlation comes out at -0.27, negative, meaning they tend to move in opposite directions. The relationship has been stable: the 1-year correlation (-0.19) sits close to the 3-year figure. The 5-year figure is -0.25, and annualized covariance runs at -1481.6 %².

VXX is close to the least connected end of CRNX's tracked universe, ranking #12 of 12. Correlation aside, the last 12 months split them widely, with CRNX ahead by 228.8 points (+179.1% versus -49.7%). One caveat on sizing: CRNX is 1.5 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CRNX vs VXX: side by side

CRNX (Crinetics Pharmaceuticals, Inc.)VXX (iPath Series B S&P 500 VIX Short-Term Futures ETN)
1-year return+179.1%-49.7%
5-year return+269.7%-95.6%
Volatility (ann.)91.7%60.9%
Beta vs S&P 5001.58-3.31
Max drawdown (3Y)-57.9%-83.3%
Market cap$9.0B
P/E (trailing)
Dividend yield0.00%0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: CRNX -57.9% vs -83.3%Higher 5y return: CRNX +269.7% vs -95.6%
-49%0%+138%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. CRNX · VXX

Year-by-year returns

YearCRNXVXX
2022-35.6%-23.8%
2023+94.4%-72.5%
2024+43.7%-26.2%
2025-9.0%-42.2%
2026+82.3%-31.6%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CRNX and VXX good diversifiers for each other?

Yes. With a correlation of -0.27, CRNX and VXX have moved largely independently, which makes them a genuinely diversifying pair by historical standards.

FAQ

What is the correlation between CRNX and VXX?

Using weekly returns as of 2026-08-27: -0.27 over 3 years, with -0.19 over the last year and -0.25 over 5 years.

Is VXX a good diversifier for CRNX?

Yes. With a correlation of -0.27, CRNX and VXX have moved largely independently, which makes them a genuinely diversifying pair by historical standards.

What does a correlation of -0.27 mean?

On the −1 to +1 scale, -0.27 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/crnx-vs-vxx.json

CRNX vs VXX: 3-year weekly correlation -0.27CRNX vs VXX-0.27

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Hubs: CRNX correlations · VXX correlations