CRDF vs VXX: Correlation
Cardiff Oncology, Inc. (CRDF) and iPath Series B S&P 500 VIX Short-Term Futures ETN (VXX) show a negative relationship: their 3-year correlation of weekly returns is -0.21.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CRDF and VXX?
Over the past 3 years, CRDF and VXX moved with a correlation of -0.21, which is negative, meaning they tend to move in opposite directions. Lately the two have drifted apart, with the 1-year correlation at -0.32 versus -0.21 over 3 years. Over 5 years the correlation is -0.23, and the annualized covariance of weekly returns is -1271.0 %².
Out of 13 assets tracked against CRDF, VXX lands near the bottom at #13. Twelve-month performance is nearly a tie, at -54.6% for CRDF and -49.7% for VXX. One caveat on sizing: CRDF is 1.6 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CRDF vs VXX: side by side
| CRDF (Cardiff Oncology, Inc.) | VXX (iPath Series B S&P 500 VIX Short-Term Futures ETN) | |
|---|---|---|
| 1-year return | -54.6% | -49.7% |
| 5-year return | -86.7% | -95.6% |
| Volatility (ann.) | 100.0% | 60.9% |
| Beta vs S&P 500 | 1.60 | -3.31 |
| Max drawdown (3Y) | -86.3% | -83.3% |
| Market cap | $0.1B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CRDF | VXX |
|---|---|---|
| 2022 | -76.7% | -23.8% |
| 2023 | +5.7% | -72.5% |
| 2024 | +193.2% | -26.2% |
| 2025 | -35.3% | -42.2% |
| 2026 | -64.9% | -31.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CRDF and VXX good diversifiers for each other?
Yes: at -0.21, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between CRDF and VXX?
The CRDF/VXX correlation stands at -0.21 on a 3-year window (1 year: -0.32, 5 years: -0.23), computed from weekly returns as of 2026-08-27.
Is VXX a good diversifier for CRDF?
Yes: at -0.21, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.21 mean?
A reading of -0.21 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/crdf-vs-vxx.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/crdf-vs-vxx/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: CRDF correlations · VXX correlations
