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COLL vs SPY: Correlation

Collegium Pharmaceutical, Inc. (COLL) and SPDR S&P 500 ETF Trust (SPY) show a weak relationship: their 3-year correlation of weekly returns is 0.16.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.16
weak
Correlation (1Y)
0.10
last 12 months
Correlation (5Y)
0.20
long-run
Ann. covariance
86.0
%² · weekly, annualized

How correlated are COLL and SPY?

Across a 3-year window, the weekly returns of COLL and SPY correlate at 0.16, weak. Little has changed lately, as the 1-year reading of 0.10 lands near the 3-year figure. Stretching to 5 years gives 0.20, with an annualized covariance of 86.0 %².

By 3-year correlation, SPY places #7 of the 15 assets tracked against COLL. Their recent paths diverged sharply: over the last 12 months SPY outperformed by 52.4 percentage points (-31.8% for COLL against +20.6% for SPY). Note the risk asymmetry: COLL runs 2.6 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

COLL vs SPY: side by side

COLL (Collegium Pharmaceutical, Inc.)SPY (SPDR S&P 500 ETF Trust)
1-year return-31.8%+20.6%
5-year return+30.2%+82.4%
Volatility (ann.)38.1%14.5%
Beta vs S&P 5000.411.00
Max drawdown (3Y)-48.4%-18.8%
Market cap$0.8B
P/E (trailing)20.8
Dividend yield0.00%1.01%
Expense ratio0.09%
Assets under management$795.3B
Sector / categoryUS ListedETF · US Large Cap
Higher yield: SPY 1.01% vs 0.00%Smaller drawdown: SPY -18.8% vs -48.4%Higher 5y return: SPY +82.4% vs +30.2%

SPY is a Large Blend fund from State Street Investment Management: $795.3B under management, 504 holdings, a 0.09% expense ratio, a 1.01% trailing dividend yield.

-31%0%+30%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. COLL · SPY

Year-by-year returns

YearCOLLSPY
2022+24.2%-18.2%
2023+32.7%+26.2%
2024-6.9%+24.9%
2025+61.6%+17.7%
2026-42.9%+13.7%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are COLL and SPY good diversifiers for each other?

Yes: at 0.16, the two have gone their own ways historically, which is what genuine diversification looks like.

FAQ

What is the correlation between COLL and SPY?

The COLL/SPY correlation stands at 0.16 on a 3-year window (1 year: 0.10, 5 years: 0.20), computed from weekly returns as of 2026-08-27.

Is SPY a good diversifier for COLL?

Yes: at 0.16, the two have gone their own ways historically, which is what genuine diversification looks like.

What does a correlation of 0.16 mean?

On the −1 to +1 scale, 0.16 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

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COLL vs SPY: 3-year weekly correlation 0.16COLL vs SPY0.16

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Hubs: COLL correlations · SPY correlations