CMPS vs PYXS: Correlation
COMPASS Pathways Plc - American Depository Shares (CMPS) and Pyxis Oncology, Inc. (PYXS) show a moderate relationship: their 3-year correlation of weekly returns is 0.41.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CMPS and PYXS?
Across a 3-year window, the weekly returns of CMPS and PYXS correlate at 0.41, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.29 versus 0.41 over 3 years. Stretching to 5 years gives 0.33, with an annualized covariance of 3964.5 %².
By 3-year correlation, PYXS places #6 of the 13 assets tracked against CMPS. Their recent paths diverged sharply: over the last 12 months CMPS outperformed by 66.1 percentage points (+210.2% for CMPS against +144.1% for PYXS). One caveat on sizing: PYXS is 1.5 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CMPS vs PYXS: side by side
| CMPS (COMPASS Pathways Plc - American Depository Shares) | PYXS (Pyxis Oncology, Inc.) | |
|---|---|---|
| 1-year return | +210.2% | +144.1% |
| 5-year return | -55.2% | -74.8% |
| Volatility (ann.) | 79.7% | 120.2% |
| Beta vs S&P 500 | 1.72 | 1.51 |
| Max drawdown (3Y) | -81.0% | -86.7% |
| Market cap | $2.0B | $0.3B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CMPS | PYXS |
|---|---|---|
| 2022 | -63.7% | -87.8% |
| 2023 | +9.0% | +34.3% |
| 2024 | -56.8% | -13.3% |
| 2025 | +82.5% | -26.3% |
| 2026 | +112.2% | +188.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CMPS and PYXS good diversifiers for each other?
Reasonably. At 0.41, CMPS and PYXS keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between CMPS and PYXS?
The CMPS/PYXS correlation stands at 0.41 on a 3-year window (1 year: 0.29, 5 years: 0.33), computed from weekly returns as of 2026-08-27.
Is PYXS a good diversifier for CMPS?
Reasonably. At 0.41, CMPS and PYXS keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.41 mean?
On the −1 to +1 scale, 0.41 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/cmps-vs-pyxs.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/cmps-vs-pyxs/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: CMPS correlations · PYXS correlations
