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CLNN vs DGX: Correlation

Clene Inc. (CLNN) and Quest Diagnostics (DGX) show a negative relationship: their 3-year correlation of weekly returns is -0.20.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.20
negative
Correlation (1Y)
-0.32
last 12 months
Correlation (5Y)
-0.15
long-run
Ann. covariance
-434.7
%² · weekly, annualized

How correlated are CLNN and DGX?

Over the past 3 years, CLNN and DGX moved with a correlation of -0.20, which is negative, meaning they tend to move in opposite directions. The link has loosened recently: the 1-year correlation (-0.32) runs below the 3-year figure (-0.20). Over 5 years the correlation is -0.15, and the annualized covariance of weekly returns is -434.7 %².

Out of 11 assets tracked against CLNN, DGX lands near the bottom at #8. Their recent paths diverged sharply: over the last 12 months DGX outperformed by 55.4 percentage points (-16.9% for CLNN against +38.5% for DGX). Risk is not evenly split, since CLNN carries 5.9 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CLNN vs DGX: side by side

CLNN (Clene Inc.)DGX (Quest Diagnostics)
1-year return-16.9%+38.5%
5-year return-97.1%+78.8%
Volatility (ann.)111.8%19.1%
Beta vs S&P 5001.720.09
Max drawdown (3Y)-84.4%-12.4%
Market cap$0.1B$27.0B
P/E (trailing)26.0
Dividend yield0.00%1.36%
Sector / categoryUS ListedHealth Care
Higher yield: DGX 1.36% vs 0.00%Smaller drawdown: DGX -12.4% vs -84.4%Higher 5y return: DGX +78.8% vs -97.1%
-32%0%+107%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). CLNN · DGX

Year-by-year returns

YearCLNNDGX
2022-75.6%-7.8%
2023-70.0%-10.1%
2024-11.5%+11.8%
2025+10.5%+17.2%
2026-23.9%+42.8%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CLNN and DGX good diversifiers for each other?

By historical standards, yes. A correlation of -0.20 means the two rarely move for the same reasons.

FAQ

What is the correlation between CLNN and DGX?

As of 2026-08-27, the correlation of weekly returns between CLNN and DGX is -0.20 over 3 years, -0.32 over 1 year and -0.15 over 5 years.

Is DGX a good diversifier for CLNN?

By historical standards, yes. A correlation of -0.20 means the two rarely move for the same reasons.

What does a correlation of -0.20 mean?

A reading of -0.20 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/clnn-vs-dgx.json

CLNN vs DGX: 3-year weekly correlation -0.20CLNN vs DGX-0.20

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Related comparisons

Hubs: CLNN correlations · DGX correlations