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CGO vs GLSI: Correlation

Calamos Global Total Return Fund - Closed End Fund (CGO) and Greenwich LifeSciences, Inc. (GLSI) show a moderate relationship: their 3-year correlation of weekly returns is 0.38.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.38
moderate
Correlation (1Y)
0.42
last 12 months
Correlation (5Y)
0.34
long-run
Ann. covariance
531.7
%² · weekly, annualized

How correlated are CGO and GLSI?

Over the past 3 years, CGO and GLSI moved with a correlation of 0.38, which is moderate. Little has changed lately, as the 1-year reading of 0.42 lands near the 3-year figure. Over 5 years the correlation is 0.34, and the annualized covariance of weekly returns is 531.7 %².

Among the 16 assets we track against CGO, GLSI sits near the bottom by co-movement, at rank #13. Their recent paths diverged sharply: over the last 12 months GLSI outperformed by 38.4 percentage points (+22.1% for CGO against +60.5% for GLSI). One caveat on sizing: GLSI is 3.8 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

CGO vs GLSI: side by side

CGO (Calamos Global Total Return Fund - Closed End Fund)GLSI (Greenwich LifeSciences, Inc.)
1-year return+22.1%+60.5%
5-year return+21.0%-52.7%
Volatility (ann.)19.2%73.1%
Beta vs S&P 5001.041.76
Max drawdown (3Y)-26.7%-61.9%
Market cap$0.1B$0.3B
P/E (trailing)2.9
Dividend yield7.31%0.00%
Sector / categoryUS ListedUS Listed
Higher yield: CGO 7.31% vs 0.00%Smaller drawdown: CGO -26.7% vs -61.9%Higher 5y return: CGO +21.0% vs -52.7%
-25%0%+175%2025-09-052026-08-27
Twelve months of weekly closes, each series rebased to 100. CGO · GLSI

Year-by-year returns

YearCGOGLSI
2022-36.6%-37.5%
2023+14.0%-30.8%
2024+36.8%+6.7%
2025+8.9%+87.1%
2026+20.3%-10.9%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are CGO and GLSI good diversifiers for each other?

A fair diversifier. At 0.38, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

FAQ

What is the correlation between CGO and GLSI?

Using weekly returns as of 2026-08-27: 0.38 over 3 years, with 0.42 over the last year and 0.34 over 5 years.

Is GLSI a good diversifier for CGO?

A fair diversifier. At 0.38, enough of each asset's movement is its own that the pair has smoothed outcomes historically.

What does a correlation of 0.38 mean?

On the −1 to +1 scale, 0.38 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.

Use this data

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CGO vs GLSI: 3-year weekly correlation 0.38CGO vs GLSI0.38

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Hubs: CGO correlations · GLSI correlations