CCCC vs RNTX: Correlation
How closely do C4 Therapeutics, Inc. (CCCC) and Rein Therapeutics, Inc. (RNTX) trade together? Their weekly returns over three years give a correlation of 0.40, which is moderate.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are CCCC and RNTX?
On 3 years of weekly data the CCCC/RNTX correlation comes out at 0.40, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.05 versus 0.40 over 3 years. The 5-year figure is 0.32, and annualized covariance runs at 7228.6 %².
By 3-year correlation, RNTX places #8 of the 19 assets tracked against CCCC. Their recent paths diverged sharply: over the last 12 months CCCC outperformed by 87.7 percentage points (+58.9% for CCCC against -28.8% for RNTX). Risk is not evenly split, since CCCC carries 1.9 times the volatility of the other side.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
CCCC vs RNTX: side by side
| CCCC (C4 Therapeutics, Inc.) | RNTX (Rein Therapeutics, Inc.) | |
|---|---|---|
| 1-year return | +58.9% | -28.8% |
| 5-year return | -90.1% | -96.4% |
| Volatility (ann.) | 184.7% | 98.8% |
| Beta vs S&P 500 | 3.22 | 1.78 |
| Max drawdown (3Y) | -90.0% | -89.7% |
| Market cap | $0.5B | $0.1B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | CCCC | RNTX |
|---|---|---|
| 2022 | -81.7% | -79.0% |
| 2023 | -4.2% | +28.6% |
| 2024 | -36.3% | -24.6% |
| 2025 | -46.9% | -49.6% |
| 2026 | +114.7% | -32.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are CCCC and RNTX good diversifiers for each other?
Reasonably. At 0.40, CCCC and RNTX keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between CCCC and RNTX?
Using weekly returns as of 2026-08-27: 0.40 over 3 years, with 0.05 over the last year and 0.32 over 5 years.
Is RNTX a good diversifier for CCCC?
Reasonably. At 0.40, CCCC and RNTX keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.40 mean?
A reading of 0.40 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
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Related comparisons
Hubs: CCCC correlations · RNTX correlations
