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AXSM vs VXZ: Correlation

How closely do Axsome Therapeutics, Inc. (AXSM) and iPath Series B S&P 500 VIX Mid-Term Futures ETN (VXZ) trade together? Their weekly returns over three years give a correlation of -0.30, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.30
negative
Correlation (1Y)
-0.06
last 12 months
Correlation (5Y)
-0.19
long-run
Ann. covariance
-307.4
%² · weekly, annualized

How correlated are AXSM and VXZ?

Across a 3-year window, the weekly returns of AXSM and VXZ correlate at -0.30, negative, meaning they tend to move in opposite directions. The link has tightened recently: the 1-year correlation (-0.06) runs above the 3-year figure (-0.30). Stretching to 5 years gives -0.19, with an annualized covariance of -307.4 %².

Among the 12 assets we track against AXSM, VXZ sits near the bottom by co-movement, at rank #11. Correlation aside, the last 12 months split them widely, with AXSM ahead by 85.4 points (+69.3% versus -16.1%). Risk is not evenly split, since AXSM carries 1.5 times the volatility of the other side.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

AXSM vs VXZ: side by side

AXSM (Axsome Therapeutics, Inc.)VXZ (iPath Series B S&P 500 VIX Mid-Term Futures ETN)
1-year return+69.3%-16.1%
5-year return+746.1%-53.1%
Volatility (ann.)39.4%25.6%
Beta vs S&P 5000.82-1.31
Max drawdown (3Y)-32.7%-36.4%
Market cap$10.8B
P/E (trailing)
Dividend yield0.00%
Sector / categoryUS ListedUS Listed
Smaller drawdown: AXSM -32.7% vs -36.4%Higher 5y return: AXSM +746.1% vs -53.1%
-16%0%+104%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. AXSM · VXZ

Year-by-year returns

YearAXSMVXZ
2022+104.2%+0.5%
2023+3.2%-44.0%
2024+6.3%-12.7%
2025+115.9%+5.7%
2026+12.9%-10.5%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are AXSM and VXZ good diversifiers for each other?

By historical standards, yes. A correlation of -0.30 means the two rarely move for the same reasons.

FAQ

What is the correlation between AXSM and VXZ?

The AXSM/VXZ correlation stands at -0.30 on a 3-year window (1 year: -0.06, 5 years: -0.19), computed from weekly returns as of 2026-08-27.

Is VXZ a good diversifier for AXSM?

By historical standards, yes. A correlation of -0.30 means the two rarely move for the same reasons.

What does a correlation of -0.30 mean?

A reading of -0.30 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/axsm-vs-vxz.json

AXSM vs VXZ: 3-year weekly correlation -0.30AXSM vs VXZ-0.30

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Related comparisons

Hubs: AXSM correlations · VXZ correlations